The use of hyperosmolar agents for intracranial hypertension was introduced in the early 20th century and remains a mainstay of therapy for patients with cerebral edema. Both animal and human studies have demonstrated the efficacy of two hyperosmolar agents, mannitol and hypertonic saline, in reducing intracranial pressure via volume redistribution, plasma expansion, rheologic modifications, an...

This paper is focused on a novel design of stepped diaphragm for MEMS capacitive pressure sensor used in tire pressure monitoring system. The structure of sensor diaphragm plays a key role for determining the sensitivity of the sensor and the non-linearity of the output.First the structures of two capacitive pressure sensors with clamped square flatdiaphragms, with different thicknesses are inv...

Sloshing due to ground motion develops large pressure on the walls of water retaining tanks. This paper evaluates the efficacy of padded walls on the reduction of sloshing effects in rectangular water storage tanks subjected to ground motion. An analytical solution based on velocity potential function is provided to obtain the response of  rigid and padded wall tanks in terms of the wave elevat...

Introduction of negative pressure wound therapy (NPWT) revolutionized the conception of wound healing. Currently, increasing number of studies confirmed the high efficiency of this therapy in many clinical scenarios. Moreover, some innovations have been introduced in recent years to improve the management of complex and chronic wounds. NPWT with instillation (NPWTi) combines traditional NPWT wi...

BACKGROUND Volume replacement with colloid solution and topical α-2 agonists may each moderate the progressive increase in intraocular pressure (IOP) during prone surgery. The authors tested the hypotheses that during prolonged prone surgery, IOP increases less with goal-directed intravenous administration of 5% albumin than with goal-directed administration of lactated Ringer's solution, and w...

The purpose of the study was to evaluate the load output of a pressure sensor in the presence of liquid saturation in a controlled environment. We hypothesized that a calibrated pressure sensor would provide diminishing load outputs over time in controlled environments of both humidified air and while submerged in saline and the sensors would reach a steady state output once saturated. A consis...

Poly(acrylic acid)-based hydrogels can swell up to 100-1000 times their own weight in desalinated water due to osmotic forces. As the swelling is about a factor of 2-12 lower in seawater-like saline solutions (4.3 wt% NaCl) than in deionized water, cyclic swelling, and shrinking can potentially be used to move a piston in an osmotic motor. Consequently, chemical energy is translated into mechan...

The interactions between water and n-perfluoroalkanes or substituted alpha-(omega-)fluoroalkanes used in blood substitute formulations were investigated experimentally and using ab initio calculations. The solubility of water in C(6)-C(9) perfluoroalkanes and five C(8) analogues of substituted fluoroalkanes was measured in the temperature range between 288 and 318 K at atmospheric pressure, usi...