The transition-metal-catalyzed amination of aryl halides has been the most powerful method for the formation of aryl amines over the past decades. Phenols are regarded as ideal alternatives to aryl halides as coupling partners in cross-couplings. An efficient palladium-catalyzed formal cross-coupling of phenols with various amines and anilines has now been developed. A variety of substituted ph...

An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.

A highly efficient and simple protocol for the synthesis of 2-amidoalkylphenols has been described. The one-pot multi-component condensation of phenols with aromatic aldehydes and amides in the presence of catalytic amount of SO3H-functionalized phthalimide (SFP) under solvent-free conditions afford the title compounds in high yields and relatively short reaction times. It is noteworthy that th...

sulphuric acid adsorbed on silica gel is a practical and useful catalyst for acetylation of varius alcohols, phenols and amines.

A novel indirect electrochemical protocol for the electroanalytical detection of phenols is presented for the first time. This methodology is demonstrated with the indirect determination of the target analytes phenol, 2-chlorophenol, 4-chlorophenol and 2,4-dichlorophenol through an electrochemically adapted optical protocol. This electrochemical adaptation allows the determination of the above ...

In analogy with the reaction of phenols very strong super acids, these compounds can be protonated by weaker acid trifluoroacetic (TFA) and trifluoromethanesulphonic (TFS) also giving rise to formation OH and/or ring products, which identified unambiguously means 1HNMR spectroscopy. The same reactions are possible deuterated acids TFA-d TFS-d. However, from reactions, additional information on ...

A mild and regioselective method for the preparation of unsymmetrical biaryl sulfides using iron(III) catalysis is described. Activation N-(arylthio)succinimides powerful Lewis acid triflimide allowed efficient thiolation a range arenes, including anisoles, phenols, acetanilides, N-heterocycles. The was applicable late-stage tyrosine tryptophan derivatives used as key step synthesis pharmaceuti...

A novel indirect electrochemical protocol for the electroanalytical detection of phenols is presented for the first time. This methodology is demonstrated with the indirect determination of the target analytes phenol, 2-chlorophenol, 4-chlorophenol and 2,4-dichlorophenol through an electrochemically adapted optical protocol. This electrochemical adaptation allows the determination of the above ...