Preimplantation genetic testing for aneuploidy (PGT-A) remains one of the most controversial topics in reproductive medicine. With more than 40% vitro fertilization cycles United States reportedly involving PGT, both those favor and opposed to PGT-A have significant interest efficacy PGT-A. Ongoing issues include what patient population, if any, benefits from PGT-A, true frequency chromosomal m...

The objective of this guideline from the Canadian Fertility and Andrology Society is to synthesize evidence on preimplantation genetic testing for aneuploidies (PGT-A) using trophectoderm biopsy 24-chromosome analysis provide clinical recommendations Grading Recommendations Assessment, Development Evaluation (GRADE) framework. To date, randomized controlled trials have been limited good-prognos...

since its first clinical application in early 90s, preimplantation genetic diagnosis (pgd) has became a powerful diagnostic procedure in clinical practice for avoiding the birth of an affected child as well as increasing the assisted reproductive technologies (art) outcome . the technique involves the screening of preimplantation embryos for chromosomal abnormalities in certain indications such...

Preimplantation genetic diagnosis (PID) is often seen as an improvement upon prenatal testing. I argue that PID may exacerbate the eugenic features of prenatal testing and make possible an expanded form of free-market eugenics. The current practice of prenatal testing is eugenic in that its aim is to reduce the numbers of people with genetic disorders. Due to social pressures and eugenic attitu...

Preimplantation diagnosis provides couples at high genetic risk the possibility of avoiding genetic disease without the need for prenatal diagnosis and selective abortion of the affected pregnancy. Following extensive background work on the reliability of genetic diagnosis in a single cell, we offered on a research basis preimplantation diagnosis to five couples at risk for offspring with the d...

CONTEXT Preimplantation genetic diagnosis (PGD) has become an option for couples for whom termination of an affected pregnancy identified by traditional prenatal diagnosis is unacceptable and is applicable to indications beyond those of prenatal diagnosis, such as HLA matching to affected siblings to provide stem cell transplantation. OBJECTIVE To describe preimplantation HLA typing, not invo...