نتایج جستجو برای: prdm16

تعداد نتایج: 242  

Journal: :Cell metabolism 2016
Katrin J Svensson Jonathan Z Long Mark P Jedrychowski Paul Cohen James C Lo Sara Serag Serkan Kir Kosaku Shinoda Julia A Tartaglia Rajesh R Rao Alain Chédotal Shingo Kajimura Steven P Gygi Bruce M Spiegelman

Activation of brown and beige fat can reduce obesity and improve glucose homeostasis through nonshivering thermogenesis. Whether brown or beige fat also secretes paracrine or endocrine factors to promote and amplify adaptive thermogenesis is not fully explored. Here we identify Slit2, a 180 kDa member of the Slit extracellular protein family, as a PRDM16-regulated secreted factor from beige fat...

2014
Anna Puig-Oliveras Maria Ballester Jordi Corominas Manuel Revilla Jordi Estellé Ana I. Fernández Yuliaxis Ramayo-Caldas Josep M. Folch

BACKGROUND Several QTLs have been identified for major economically relevant traits in livestock, such as growth and meat quality, revealing the complex genetic architecture of these traits. The use of network approaches considering the interactions of multiple molecules and traits provides useful insights into the molecular underpinnings of complex traits. Here, a network based methodology, na...

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2007

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