HIV-1 aspartyl protease (PR) plays a key role in virion morphogenesis, underscoring the effectiveness of protease inhibitors (PI). Despite their utility, side effects and drug-resistance remains a problem. We report the development of RNA aptamers as inhibitors of HIV-1 PR for potential use in anti-HIV gene therapy. Employing Systematic Evolution of Ligands by Exponential Enrichment (SELEX), we...

We report on a Ag5 coordination polymer and discrete Ag8 and Ag10 dithiophosphate clusters. The cluster formation and structures were affected by the stoichiometric control of the M : L molar ratios used. The cluster [Ag5{S2P(O(i)Pr)2}4]n(PF6)n, , is a monomeric unit within a coordination polymer formed through the reaction between [Ag(CH3CN)4]PF6 and the dithiophosphate ligand, [S2P(O(i)Pr)2](...

Definition 1. A language L ∈ BQP if there exists a classical polynomial time algorithm A that maps inputs x ∈ {0, 1}∗ to quantum circuits Cx on n = poly(|x|) qubits, where the circuit is considered a sequence of unitary operators each on 2 qubits, i.e Cx = UTUT−1...U1 where each Ui ∈ L ( C2 ⊗C2 ) , such that: i. Completeness: x ∈ L⇒ Pr(Cx accepts |0n〉) ≥ 2 3 ii. Soundness: x 6∈ L⇒ Pr(Cx accepts...

The forests in Sardasht area in the West Azarbaijan Province were quantitatively studied in this research. Based on Importance Value Index, in general, two types of forests have been identified: Quercus libani Oliv. in the northern, northeastern and northwestern aspects and Quercus brantii Lindl. in the southern, southeastern and southwestern and eastern aspects. The mean of vegetation crown pe...

We report results from high Prandtl number turbulent thermal convection experiments. The viscous boundary layer and the Reynolds number are measured in four different fluids over wide ranges of the Prandtl number Pr and the Rayleigh number Ra, all in a single convection cell of unity aspect ratio. We find that the normalized viscous layer thickness may be represented as delta(v)/L=0.65Pr(0.24)R...

Quadrature mirror filter (QMF) banks are essential building blocks of a subband/transform coder. Generally, one wants the filter bank to have the perfect reconstruction (PR) property, which means that, in absence of coding, a delayed copy of the original signal is reconstructed exactly in the critically-sampled analysis-synthesis system of Fig. 1. Although there are useful filter banks that are...

M. S. Santos, J. D. Szezech Jr, F. S. Borges, K. C. Iarosz, I. L. Caldas, A. M. Batista, R. L. Viana, J. Kurths Pós-Graduação em Ciências, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil. Departamento de Matemática e Estat́ıstica, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil. Instituto de F́ısica, Universidade de São Paulo, São Paulo, SP, Brazil. Departamento de...

Compliance with U.S. Department of Agriculture (USDA) composition-based labeling standards often has been regarded as evidence of the shelf stability of ready-to-eat (RTE) meats. However, the USDA now requires further proof of shelf stability. Our previous work included development of equations for predicting the probability of Staphylococcus aureus growth based on the pH and a(w) of an RTE pro...