Cadmium is a highly toxic metal that can damage a number of organs including the gastrointestinal tract. It has been shown that cadmium partially reduces L-threonine intestinal absorption probably by binding to membrane proteins which pertain to active transport systems or are functionally related to them. Calcium, however, is an essential element in a wide variety of cellular activities. The a...

This study evaluated the effects of sodium chloride reduction and replacement with potassium chloride or modified potassium chloride based salts using a weight or molar equivalent basis on the sensory and physico-chemical properties of pork sausage patties. Three independent replications of pork sausage patties were manufactured to compare five treatments: full sodium, reduced sodium, modified ...

Cytotoxicity of cadmium sulphide, oxide and chloride was tested using A549 and CHO-9 cells. Metabolic activity of cells (MTT test) and cell membrane permeability (NRU test) were used as cytotoxicity endpoints. The results revealed unexpectedly low toxicity of cadmium sulphide as compared to chloride and oxide. This preliminary report does not provide any explanation for this effect, but the res...

Duck red cells in hypertonic media experience rapid osmotic shrinkage followed by gradual reswelling back toward their original volume. This uptake of salt and water is self limiting and demands a specific ionic composition of the external solution. Although ouabain (10(-4)M) alters the pattern of cation accumulation from predominantly potassium to sodium, it does not affect the rate of the rea...

The present study was designed to investigate the potential protective effect of Coenzyme Q10 against the testicular toxicity of cadmium in male rabbits. Four groups of animals were used in this study (control, Coenzyme Q10, cadmium chloride-treated (5 mg/kg), cadmium chloride plus Coenzyme Q10 (10 mg/kg) for 30 days). Results showed normal testicular tissue in control and coenzyme Q10 groups. ...

Background: The protective effects of Montelukast (Mont), as an anti-inflammatory drug, against cadmium-induced kidney cell damage have already been studied and identified. Since the significant part cadmium nephrotoxicity is caused by oxidative stress, this in vivo vitro study was conducted to investigate possible role antioxidant properties protection. Methods: In section, 42 rats were treate...

nickel and cadmium are heavy metals with some hazards for plant metabolism. the impacts of nickel chloride (0, 400 and 800 μm) in the presence of vitamin b complex (0, 30 and 60 ml from pharmacy commercial stock) and the impacts of cadmium chloride (0, 100, 200, 300, 400, 500 and 600 μl from 100 µm stock) in pot and cadmium nitrate (0, 100, 200, 400, 800, 1600 and 3200 μl from 100 µm stock) in ...

OBJECTIVE To study the effects of cadmium on hepatocellular DNA damage, expression of proto-oncogenes c-myc, c-fos, and c-jun as well as apoptosis in rats. METHODS Cadmium chloride at the doses of 5, 10, and 20 micromol/kg was given to rats by i.p. and there were 5 male SD rats in each group. Hepatocellular DNA damage was measured by single cell gel electrophoresis (or comet assay), while exp...