Perimenopause is an imprecise period in woman over 40 years of age, which comprises the time between the moment that the first changes in the menstrual cycle appear and the year following the definitive cessation of the menses. Besides irregular bleeding, many women also complain of hot flashes and other characteristic symptoms of postmenopause. Moreover, most of them are concerned about the fu...

PURPOSE to generate and validate a proper questionnaire to evaluate the sexual function in post-menopause women. METHODS 251 women, within 2 to 15 years postmenopause, were included in the study. Questionnaire's reproductibility/reliability was evaluated by Pearson, intraclass and Lin's correlation coefficients. The internal consistance was examined by the Cronbach's alpha coefficient. Classi...

UNLABELLED Hormones such as estrogen, progesterone and prolactin are implicated in anumber of ways as possible causes of breast cancer. Throughout women life cycle, breast development and function depend on complex critical interplay of these hormones. The acknowledged gaps in our understanding concerning progesterone, estrogen and prolactin hormones involvement in human breast cancer has expos...

This review presents epidemiological data on the effect of sex hormones and reproductive status level blood pressure (BP) incidence es­sential hypertension (EHT) in women. The role estrogen deprivation hyper­androgenism development EHT peri- postmenopause is discussed. main mechanisms periand postmenopausal women: sympathetic renin-angiotensin-aldosterone system hyperactivity, salt-sensitivity,...

The frequency of female sexual dysfunction increases with age, and the menopausal transition has a negative effect on the sexuality. Pharmacological treatment options for female sexual dysfunction during the peri- and post-menopause include hormone therapy or sildenafil. A limited number of randomized, controlled trials have been conducted and evidence suggests that systemic hormone therapy wit...