Neuropathic pain (NP), a common form of human pain, often poorly responds to analgesic medications. In this review the authors discuss the pathophysiology and conventional treatment of neuropathic pain and provide evidenced-based statements on the efficacy of botulinum neurotoxins (BoNTs) in this form of pain. The level of efficacy for BoNT treatment in each category of NP is defined according ...

BACKGROUND Postherpetic neuralgia is spontaneous pain and allodynia that persist long after the disappearance of the cutaneous lesions caused by herpes zoster. Inoculation of mice with herpes simplex virus-1 causes herpes zoster-like skin lesions and herpetic and postherpetic pain. Although NMDA receptors have been suggested to be involved in postherpetic pain as in other types of neuropathic p...

www.pjonline.com For personal use only. Not to be reproduced without permission of the editor ([email protected]) Coinuing prossional deelopm nt Identify knowledge gaps 1. What are the possible complications of chickenpox? 2. What should a pregnant woman with no history of chickenpox do if she comes into contact with the varicella zoster virus? 3. What is postherpetic neuralgia and how ...