Two related methods exist for sampling from posterior distributions of the MLE with a known prior Newton & Raftery (1994) [8], Efron (2011) [4]. We compare them by examining asymptotic Edgeworth expansions of their pivotal distributions. The result is that Newton & Raftery (1994) is 2nd order consistent to the posterior distribution with prior proportional to the Fisher Information, under some ...

In our previous studies, we noted a non-uniform distribution of protein tracer preferentially entering the anterior stromal lamellae of the cornea from the limbus. Given other differences reported previously between the anterior and posterior lamellae of the cornea, and the number of corneal disorders in which abnormalities are preferentially confined to either the anterior or posterior lamella...

conclusion safety-related parameters of posterolateral and posterior approaches in supine thoracentesis are far better than that of the conventional lateral approach. background in patients who have difficulty sitting, thoracentesis is attempted in a supine position via lateral approach. recently, a new table has been designed for supine thoracentesis. this table has gaps that allow access to t...

the standard approach to management of high imperforate anus is colostomy in the newborn period followed by posterior saggital anorectoplasty (psarp) at 6 to 12 months of age. the purpose of this study was to determine whether a one-stage repair by primary psarp in the newborn period could be performed without clear determent to the patient’s functional result. totally 30 newborns with high imp...

A hierarchical Bayesian model is investigated. This model can accommodate study heterogeneity in metaanalyses. The joint posterior distribution is derived by multiplying the likelihood and priors on this model. The conditional posterior distribution of all parameters is obtained for Gibbs sampler algorithm. A simulation study is then performed to demonstrate the validity of the Gibbs sampler in...

in recent years, some statisticians have studied the signal detection problem by using the random field theory. in this paper we have considered point estimation of the gaussian scale space random field parameters in the bayesian approach. since the posterior distribution for the parameters of interest dose not have a closed form, we introduce the markov chain monte carlo (mcmc) algorithm to ap...

abstract a patient with a 3-month history of headache refractory to pain medication was admitted. the ct scan and mri showed evidence of a posterior fossa mass. this was pathologically confirmed as an extra medullary plasmacytoma (emp). he had a pathologic fracture of the left humerus 7 years ago while the radiologist was unaware at the time of diagnosis. a solitary bone plasmacytoma (sbp) was ...

a lot of researches have investigated the effects of topical cyclosporine a on the eye surface layers' diseases. by now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. the aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. to reach higher corneal dru...