PURPOSE Up to 75% of women experience hot flashes, which can negatively impact quality of life. As hot flash physiology is not definitively understood, it cannot be assumed that effective agents represent class effects. Therefore, there is a continued need for rigorous evaluation to identify effective nonhormonal options for hot flash relief. METHODS A randomized, double-blind trial evaluated...

PURPOSE/OBJECTIVES To evaluate the intermediate term efficacy and toxicity of the use of venlafaxine for the control of hot flashes. DESIGN An open-label continuation phase study following a double-blind, randomized, placebo-controlled clinical trial that tested three doses of venlafaxine for the control of hot flashes. SETTING North Central Cancer Treatment Group institutions. SAMPLE 102...

background: osteoporosis is a chronic disease that contributes substantially to decrease physical activity and decline in the quality of life. osteoporosis can be diagnosed easily with the use of dual-energy x-ray absorptiometry (dxa) equipment. the aim of this study was to investigate the magnitude of bone loss on proximal femur and lumbar spine ls in pre- and post-menopausal women from isfaha...

Numerous reports in the medical literature and popular media have discussed the effectiveness of various nonhormonal agents in reducing menopausal hot flash symptoms. Data for these therapies are limited, and most of the studies have been conducted in women with a history of breast cancer. Selective serotonin reuptake inhibitors and venlafaxine have been shown to reduce hot flashes by 19 to 60 ...

INTRODUCTION Hot flashes have been postulated to be linked to the development of metabolic disorders. This study aimed to evaluate the relationship between hot flashes, adipocyte-derived hormones, and insulin resistance in healthy, non-obese postmenopausal women. PARTICIPANTS AND DESIGN In this cross-sectional study, a total of 151 women aged 45-60 years were stratified into one of three grou...

Objectives The aims of the research are to examine the problems of abnormal menopausal women: the relationship between depression and menopausal-specific quality of life (MENQOL)-symptoms among postmenopausal women; the association of MENQOL-symptoms between pre- and postmenopausal female society in Bangladeshi real community. Methods This cross sectional study was conducted on 435 women of T...

This study examined the differences in psychophysiological responses during mental task performance between women with (Group S) and without (Group A) menopausal hot flashes. Twelve women who reported experiencing daily moderate or severe menopausal hot flashes (Group S) and twelve women who reported having no hot flashes (Group A) participated in a mental arithmetic (Task) and a control (Non-t...

OBJECTIVE To identify risk factors associated with the duration of hot flashes and the time of peak hot flash severity in mid-life women. METHODS A cohort of 647 women reporting hot flashes were followed for 1-7 years, with survey data and hormone measurements. Survival analysis determined the association of risk factors with the duration of hot flashes. Linear regression determined the assoc...

OBJECTIVE The aim of this study was to examine the associations of demographic characteristics, health behaviors, and hormone concentrations with the experience of any, current, more severe, and more frequent midlife hot flashes. METHODS Baseline data from 732 women aged 45 to 54 years who were enrolled in the Midlife Women's Health Study were analyzed. A clinic visit was conducted to collect...