Portal vein thrombosis is common in cirrhotic patients and results in increased morbidity and mortality. Transjugular intrahepatic portosystemic shunt (TIPS) creation is a well-established therapy for refractory variceal bleeding and refractory ascites in patients who do not tolerate repeated large volume paracentesis. Experience and technical improvements have led to improved TIPS outcomes tha...

For transplant surgeons, end-stage liver disease with portal venous thrombosis and a previous splenorenal shunt (SRS) is a significant challenge during liver transplantation. Thrombosis of the portal vein can be corrected by surgical interventions, such as portal venous thrombectomy or surgical removal of the thrombosed portal vein. Even also placement of a graft between the mesenteric vein and...

Portal vein thrombosis is a rare but life-threatening complication during pregnancy and postpartum period. Color Doppler ultrasound is useful for prompt diagnosis. Although the risk of complications should be considered, successful pregnancy with comorbid portal vein thrombosis is possible with appropriate anticoagulation therapy and close monitoring.

Neonatal cerebral infarction is a serious and disabling condition. It is extremely rare if it occurs in association with portal vein thrombosis. We are reporting 2 cases of neonatal cerebral infarction with this etiology. The unique mechanism of cerebral infarction will be discussed. We propose that in the absence of any identifiable cause for the cerebral infarction, portal vein thrombosis sho...

The protein C system is essential in limiting the activation of coagulation in vivo. We report the case of a 45 year old man with portal vein thrombosis complicated by ruptured oesophageal varices. Low concentration of plasma protein C was found in the patient and subsequently in one brother with a history of venous thromboembolism, and also in one son and one nephew who were asymptomatic. Here...

The most common cause of portal hypertension is liver cirrhosis and other common causes are portal vein obstruction, idiopathies or it may associate with infection, pancreatitis or abdominal trauma. Also hematological malignancies and other hypercoagulable states are rarely related with portal vein thrombosis and portal hypertension. Antiphospholipid syndrome (APS) is a clinical syndrome consis...

Background Portal vein thrombosis (PVT) is one of the most common causes of extrahepatic portal hypertension in children, which may follow neonatal umbilical vein catheterization. The incidence rates of catheter-related PVT, in infants and children vary in different studies. This study aimed to determine PVT incidence in the children under 3 years old with a history of neonatal umbilical vein c...

BrMedJ 1990;300:590-2 Portal vein thrombosis may be the first presentation of a hypercoagulable state. We report a case that illustrates a diagnostic approach to show the extent of the splanchnic venous thrombus and to investigate its haematological aetiology. The discussion focused on the association between portal vein thrombosis and myeloproliferative disease and controversies in managing th...

showed portal vein thrombosis with progression to superior and inferior mesenteric vein and splenic vein (Figure 1). Antithrombin III, protein C and S were normal; lupus anticoagulant 1.19 (<1.2); anticardiolipin antibody was positive (IgG 30.5/IgM 50: <10). Our patient meets the criteria for SLE and for APS [1,4]. APS is characterized by lupus anticoagulant, anticardiolipin antibodies, vascula...

BACKGROUND Splanchnic vein thrombosis may complicate inherited thrombotic disorders. Acute cytomegalovirus infection is a rare cause of acquired venous thrombosis in the portal or mesenteric territory, but has never been described extending into a main hepatic vein. CASE PRESENTATION A 36-year-old immunocompetent woman presented with acute primary cytomegalovirus infection in association with...