Abstract 57-year-old Caucasian female presented with depression, apathy, and personality changes a markedly “flaccid face”. A computerized tomography (CT scan) revealed remarkable bilateral hyperostosis frontalis interna significant frontal lobe compression. definitive operative procedure craniotomies was undertaken to relieve compression prevent further complications. During surgery, the bone ...
HLA A, B, and C antigens were studied in 25 patients with ankylosing hyperostosis. There was no evidence of an increased frequency of any antigen in association with the condition itself. However, a high frequency of several antigens was found, reflecting the predominance of Jewish patients in the series.