Network models are an effective means of incorporatingpore-scale heterogeneity into flow models of porous materials. The drawback to these models used to be the inability to obtain quantitative macroscopic parameters representing larger (experimental-scale) media. However, recently developed modeling techniques, combined with more widely available computational resources, make the simulation of...

The cortical actin network is dynamically rearranged during secretory processes. Nevertheless, it is unclear how de novo actin polymerization and the disruption of the preexisting actin network control transmitter release. Here we show that in bovine adrenal chromaffin cells, both formation of new actin filaments and disruption of the preexisting cortical actin network are induced by Ca2+ conce...

   In this study, linearized transport pore model (LTPM) is applied for modeling nanofiltration (NF) membrane separation process. This modeling approach is based on the modified extended Nernst-Planck equation enhanced by Debye-Huckel theory to take into account the variations of activity coefficient especially at high salt concentrations. Rejection of single-salt (NaCl) electrolyte is inve...

Microscopic structures of porous media are mainly reconstructed using physical experimental methods and numerical reconstruction methods. However, their accuracy is closely related to the resolution of real rock core images and polishing techniques of core chips amongst others, which significantly limit the development of micro-network flow simulation. In this paper, we proposed a new method fo...

The bacterial cell wall is a network of sugar strands crosslinked by peptides that serve as the primary structure for bearing osmotic stress. Despite its importance in cellular survival, the robustness of the cell wall to network defects has been relatively unexplored. Treatment of the gram-negative bacterium Escherichia coli with the antibiotic vancomycin, which disrupts the crosslinking of ne...

We present a pore-scale network model of twoand three-phase flow in disordered porous media. The model reads three-dimensional pore networks representing the pore space in different porous materials. It simulates wide range of twoand three-phase pore-scale displacements in porous media with mixed-wet wettability. The networks are composed of pores and throats with circular and angular cross sec...

A two-dimensional pore-scale numerical model was developed to evaluate the dynamics of preferential flow paths in porous media caused by bioclogging. The liquid flow and solute transport through the pore network were coupled with a biofilm model including biomass attachment, growth, decay, lysis, and detachment. Blocking of all but one flow path was obtained under constant liquid inlet flow rat...

Pore fluid pressure in a fault zone can be altered by natural processes (e.g., mineral dehydration and thermal pressurization) and industrial operations involving subsurface fluid injection and extraction for the development of energy and water resources. However, the effect of pore pressure change on the stability and slip motion of a preexisting geologic fault remains poorly understood; yet, ...