Hepatocellular carcinoma (HCC) remains a major public health problem. Transarterial chemoembolization (TACE) is recognized as the standard of care for patients with unresectable, asymptomatic, noninvasive and multinodular HCC. This procedure is based on percutaneous administration of a cytotoxic drug emulsified with Lipiodol followed by embolization of the tumour-feeding arteries. The standard ...

Kristin Persson,1 Yoyo Hinuma,2 Ying Shirley Meng,2 Anton Van der Ven,3 and Gerbrand Ceder4 1Lawrence Berkeley National Laboratory, 1 Cyclotron Rd., Berkeley, California 94720, USA 2University of California–San Diego, Atkinson Hall 2703, La Jolla, California 92093, USA 3University of Michigan, Ann Arbor, Michigan 48109, USA 4Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambri...

In this paper, a floating tonal reduplicant suffix is proposed to re-analyze Changzhi Chinese suffix tone sandhi (Hou 1983), which has been presented as major evidence for Contour Tone Units (CTU). All stem contour tones in Changzhi, except one stem level tone, overwrite the underlying tone (HMH) of the adjectival and diminutive suffixes. In Yip (1980, 1989), this process was analyzed as spread...

DRUG ADDIcTIoN, especially through the use of poppy (Papaver somniferum Linn.) and hemp (Cannabis sativa Linn.), is the main concern of this paper. Although the use of these two plants in medieval Islam was extensive, yet little has been written on this timely subject by historians of medicine and pharmacology. Consulting contemporary original sources, it is my hope to sketch a history of their...

Ancient Egyptian and Greek pharmacopoeias reveal frequent use of different drugs, somniferous or narcotic, which contain poisonous elements. Among the toxic plants enumerated by Dioscorides, we find poppy and others. Egyptians were fond of taking these narcotic or euphoric substances attributed to nepenthes, but it is difficult to prove whether ancient people were aware of modern aspects of add...

To the Editor: The incidence of food allergy is age dependent, particularly affecting children and young patients. When selfreported, it ranges between 3% and 35%. However, placebocontrolled food challenge is positive in just 1% to 4% of all suspected cases. In elderly, anaphylactic reactions tend to be less severe, and a primary manifestation at this age is unusual. A 70-year-old white man nee...

Weasels may be cunning, we might admire the intelligence of dogs and cats, but we can be forgiven for expecting the jumping spider, a diminutive predator with a brain not much bigger than a poppy seed, to be one of Descartes’ automatons. Yet, jumping spiders, also known as salticids, alternate between entertaining and alarming us by planning prey-capture tactics ahead of time, adjusting their h...