Results In total, 866 prescriptions were examined. The overall prevalence of prescription modifications was 17.9% (155/866), with a mean of 31 modifications per week. Prescription only medicines (POM) comprised 147 (94.8%) of the modifications, 128 (87.1%) of which concerned a prescription error requiring a simple clerical clarification before dispensing could occur, with the remaining 19 (12.9...

Pyrrolidine-amide oligonucleotide mimics (POMs) exhibit promising properties for potential applications, including in vivo DNA and RNA targeting, diagnostics and bioanalysis. Before POMs can be evaluated in these applications it is first necessary to synthesise and establish the properties of fully modified oligomers, with biologically relevant mixed sequences. Accordingly, Boc-Z-protected thym...

The hybridization of polyoxometalates (POMs) through an organic-inorganic association offers several processing advantages in the design of heterogeneous catalysts. A clear understanding of the organization of these hybrid materials on solid surfaces is necessary to optimise their properties. Herein, we report for the first time the organization of Keggin phosphotungstic [PW12O40](3-) and Wells...

The landscapes colonized by invasive earthworms in the eastern U.S. are often patchworks of forest stands in various stages of successional development. We established six field sites in tulip poplar dominated forests in the Smithsonian Environmental Research Center in Edgewater, MD, that span mid (50–70 years-three plots) and late (120– 150 years-three plots) successional stages where younger ...

Uptake of atmospheric CO2 by the oceans and the export of carbon into deeper waters via the biological CO2 pump is driven by the production of particulate organic matter (POM). The elemental ratios of carbon, nitrogen, and phosphorus within POM follow Redfield ratios, suggesting that the concentrations of dissolved inorganic carbon (DIC) and nutrients decrease during new production correspondin...

About 10 years ago, a sexually differentiated nucleus was identified in the preoptic area (POA) of the Japanese quail in the course of studies analyzing the dimorphic mechanisms involved in the activation of sexual behavior. In this species, males exposed to testosterone copulate while females never show this masculine behavior. The present paper reviews anatomical, neurochemical, and functiona...

The first passage of stool after birth (meconium), is delayed in preterm neonates compared to term neonates. Ninety-nine percent of term infants and 76% of premature infants pass a stool in the first 24 hours of life. Ninety-nine percent of premature infants pass a stool by 48 hours. To explain the effect of some factors on the time of first passage of meconium(POM) in neonates. Between January...

A simple and facile one-step method for the synthesis of an organic dye-functionalized polyoxometalate (POM) hybrid with visible-light photo-response was reported. The POM hybrid was fully characterized via single crystal XRD, powder XRD, FTIR and elemental analysis. The reaction of the organic dye with inorganic salts gave the dye-functionalized POM (MoBB3), in which the POM cluster was formed...

Retinoic acid receptor (RAR) signaling is required for morphogenesis of the ventral optic cup and closure of the choroid fissure, but the mechanisms by which this pathway regulates ventral eye development remain controversial and poorly understood. Although previous studies have implicated neural crest-derived periocular mesenchyme (POM) as the critical target of RA action in the eye, we show h...

BACKGROUND To support decisions about surgical treatment of elderly patients with cancer, population-based estimates of postoperative mortality (POM) rates are required. METHODS Electronic records from the Rotterdam Cancer Registry were retrieved for octogenarians and nonagenarians who underwent resection in the period 1987-2000. POM was defined as death within 30 days of resection and both e...