The purpose of this study is to develop and characterize the nature of a solid dispersion system of nifedipine in a polymer matrix consisting of PVP K30 and poloxamer 407. Dispersions consist of drug, polymeric carrier and surfactant carrier. Binary solid dispersions consisting of nifedipine and PVP K30 were developed by solvent evaporation method. Poloxamer 407, surfactant carrier was incorpor...

We developed solid dispersions, using the gas anti-solvent technique (GAS), to improve the oral bioavailability of the poorly water-soluble active component oridonin. The solubility of oridonin in supercritical carbon dioxide was measured under various pressures and temperatures. To prepare oridonin solid dispersions using the GAS technique, ethanol was used as the solvent, CO(2) was used as th...

Polyurethane/zeolite 13X nanocomposite films were fabricated using solution casting method. The synthesized nanocomposite films were structurally characterized using SEM, TGA and tensile analysis. SEM images showed appropriate distribution of nanocrystalline zeolite particles within polyurethane matrix. Better thermal stability of nanocomposite films in comparison to neat polyurethane was shown...

Polyurethane-immobilized Flavobacterium cells (ATCC 39723) degraded pentachlorophenol (PCP) at initial concentrations as high as 300 mg liter-1. The reversible binding of PCP to the polyurethane was shown to be important in the protection of the cells from inhibition of PCP degradation. The degradation activity of the bacteria was monitored for 150 days in semicontinuous batch reactors. The deg...

The filtration behaviour of some clay–water dispersions was studied. Two Spanish fibrous phyllosilicates (sepiolite from Vicálvaro and palygorskite from Turón) and a commercial bentonite (Bentopharm©, UK) with similar sizes and different morphologies (fibrous and/or laminar) were selected as model clays. Sepiolite from Vicálvaro is an almost pure fibrous sample, Bentopharm© presents a high amou...

A sensitive methodology for PCR detection of Staphylococcus aureus or Bordetella pertussis DNA within cot mattress polyurethane foam was developed. The assay's applicability was evaluated on polyurethane foam from used cot mattresses. S. aureus DNA was detected in 42% of mattresses of sudden infant death syndrome (SIDS) victims and 29% of comparison group (no death) mattresses tested. B. pertus...

A sensitive methodology for PCR detection of Staphylococcus aureus or Bordetella pertussis DNA within cot mattress polyurethane foam was developed. The assay's applicability was evaluated on polyurethane foam from used cot mattresses. S. aureus DNA was detected in 42% of mattresses of sudden infant death syndrome (SIDS) victims and 29% of comparison group (no death) mattresses tested. B. pertus...