BACKGROUND Little is known about prescribing appropriateness for community-dwelling people with dementia (PWD). OBJECTIVE To estimate potentially inappropriate prescribing (PIP) prevalence among PWD in primary care in Northern Ireland, and to investigate associations between PIP, polypharmacy, age, and gender. METHODS A retrospective cross-sectional study was conducted, using data from the ...

BACKGROUND Antipsychotic prescription information is commonly derived from structured fields in clinical health records. However, utilising diverse and comprehensive sources of information is especially important when investigating less frequent patterns of medication prescribing such as antipsychotic polypharmacy (APP). This study describes and evaluates a novel method of extracting APP data f...

BACKGROUND/AIM Prescription of drugs is a fundamental care component of the elderly. Elderly patients often take multiple drugs, and it is known that polypharmacy may lead to drug interactions and adverse events. The aim of this study was to analyze the long-term drug use and the prevalence of polypharmacy among the elderly population in the Republic of Srpska, Bosnia and Herzegovina. METHODS; ...

OBJECTIVE To elucidate the associations between polypharmacy and age- and gender-specific risks of admission for fall-related fractures. DESIGN Nested case-control study. SETTING This analysis was randomly selected from all elderly beneficiaries in 2007-2008, and represents some 30% of the whole older insurers using Taiwan's National Health Insurance Research Database. PARTICIPANTS We ide...

Polypharmacy is common in the elderly due to multimorbidity and interventions. However, the temporal association between polypharmacy and renal outcomes is rarely addressed and recognized. We investigated the association between cardiovascular (CV) polypharmacy and the risk of acute kidney injury (AKI) in elderly patients.We used the Taiwan National Health Insurance PharmaCloud system to invest...

Objectives: The aim of this study was to investigate the prevalence and its determinants of Antipsychotic Use in patients with psychiatric disorders. Materials and Methods: This study was on patients with psychiatric disorder that have discharged from the hospital. We have assessed all patients with psychiatric interview and evaluation of their psychiatric documentations. Results: 90.7% o...

Polypharmacy can occur in people of all ages but is typically more prevalent among older adults. This population often has multiple morbidities and is thus at high risk for polypharmacy and adverse drug events (Hajjar, Cafiero, & Hanlon, 2007; Hanlon et al., 1997). In addition to concerns about patient safety, the health costs of polypharmacy can quickly compound. Older adults account for more ...

CONTEXT Medications are taken to ease, control or cure ailments. They are effective and safe if used correctly. In the elderly, disorders that occur as a result of ageing, frequently require treatment, resulting in increased use of medications. Polypharmacy is common among the elderly and although it can be therapeutic in nature, is linked to adverse events such as falls. EVIDENCE ACQUISITION...