A quantitative comparison of two full three-dimensional (3D) gel dosimetry techniques was assessed in a clinical setting: radiochromic gel dosimetry with an in-house developed optical laser CT scanner and polymer gel dosimetry with magnetic resonance imaging (MRI). To benchmark both gel dosimeters, they were exposed to a 6 MV photon beam and the depth dose was compared against a diamond detecto...

*Corresponding author: Dr. Tayyeb Allahverdi Pourfallah, Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran. Fax: +98 21 88973653 E-mail: [email protected] Background: Polymer gel dosimetry is still the only dosimetry method for direct measuring of threedimensional dose distributions. MRI Polymer gel dosimeters are tissue equi...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

In this study the spectrophotometric response of the Toluidine Blue O (TBO)-gelatin gel dosimeter irradiated with gamma rays was characterized. Preparation of dyed-gelatin gel takes place in neutral medium; to give eventually gel dosimeter has a sharp absorbance peak at 635 nm that bleaches quantitatively upon irradiation and the colour change can be measured with UV-VIS spectrophotometer. The ...

background: the compositions of ferrous sulphate, agarose and xylenol orange dye (fax) and ferrous sulphate, gelatin and xylenol orange dye (fgx) in solution of distilled water and sulphuric acid are two tissue-equivalent gel dosimeters. ionizing radiation causes oxidation of fe2+ ion to fe3+ ions which diffuse through the gel matrix and blur the image of absorbed dose over a period of hours af...

The polymer gel-Magnetic Resonance Imaging (MRI) dosimetry technique was employed to evaluate the mechanical and dose delivery accuracy in Leksell gamma knife stereotactic radiosurgery for the treatment of multiple targets. Two different polymer gel dosimeter formulations that have been reported in the literature were prepared in-house. A plan for the treatment of four brain metastases (targets...

We report the design and synthesis of a tetraphenylethene substituted with naphthalimide at the 4, 6 positions, named NI-2TPE. NI-2TPE exhibits strong solvent-dependent emission properties with combined ICT and AIE characteristics in THF-H2O systems. This probe was used directly on test papers to distinguish normal organic solvents using their emission colours under UV light based on its AIE an...

Environmentally responsive, water-soluble polymers have a wide variety of uses ranging from drug delivery to viscosity modifiers. Their utility lies in the ability to use environmental perturbations to dramatically alter the material properties. Here, we describe the interfacial properties of a hydrophobically modified copolymer of N-isopropylacrylamide and glycinylacrylamide (NIPAM-N-Gly-(C18)...

The BANG (MGS Research Inc., Guilford, CT) polymer gel has been used as a dosimeter to determine the three-dimensional (3D) dose distribution of a ruthenium-106 (Ru-106) ophthalmologic applicator. An eye phantom made of the BANG gel was irradiated with the Ru-106 source for up to 1 h. The phantom and a set of calibration vials were scanned simultaneously in a GE 1.5 T MR imager using the Hahn s...