نتایج جستجو برای: polymer conjugation
تعداد نتایج: 106040 فیلتر نتایج به سال:
We investigated a series of Tween 85 modified low molecular weight polyethylenimine (LPEI, 0.8k/1.2k/2.0k)-copolymers (Zs) through simple formulation and covalent conjugation with phosphorodiamidate morpholino oligomer (PMO) for their potential to enhance delivery in vitro and in dystrophic mdx mice. Z polymers significantly enhanced PMO-induced exon-skipping in a GFP reporter-based cell cultur...
We report a simple temperature-responsive bioconjugate system comprising superfolder green fluorescent protein (sfGFP) decorated with poly[(oligo ethylene glycol) methyl ether methacrylate] (PEGMA) polymers. We used amber suppression to site-specifically incorporate the non-canonical azide-functional amino acid p-azidophenylalanine (pAzF) into sfGFP at different positions. The azide moiety on m...
We present a new class of polymeric ligands for quantum dot (QD) water solubilization to yield biocompatible and derivatizable QDs with compact size (approximately 10-12 nm diameter), high quantum yields (>50%), excellent stability across a large pH range (pH 5-10.5), and low nonspecific binding. To address the fundamental problem of thiol instability in traditional ligand exchange systems, the...
A lot of solid tumors are characterized by uncontrolled signal transduction triggered by receptors related to cellular growth. The targeting of these cell receptors with antitumor drugs is essential to improve chemotherapy efficacy. This can be achieved by conjugation of an active targeting agent to the polymer portion of a colloidal drug delivery system loaded with an antitumor drug. The goal ...
r-phycoerythrin (r-pe), a fluorescent protein from phycobiliprotein family, is isolated from red algae. conjugation of antibodies to r-pe facilitates multiple fluorescent staining methods. in the present study polyclonal antibodies and polyclonal f(ab')2 fragment antibodies were conjugated to r-pe by two different methods. the efficiency of the methods was evaluated using immunocytochemistry (i...
چکیده ندارد.
INTRODUCTION Conjugated polymers show intriguing properties such as electrical conductivity,1–4 electroluminescence5–9 and chemical-sensing ability.10–12 Synthesis of new conjugated polymers is an important subject in polymer chemistry as well as in material chemistry, owing to their potential applications in optoelectronic devices. Generally, p-electrons are delocalized throughout the conjugat...
Immobilization of enzymes is interesting research topic from both fundamental and applied aspects, and various kinds of immobilization methods including chemical and physical procedures have been actively investigated, e.g. the chemical conjugation of enzyme with water-soluble polymers and the physical entrapment into polymer gel matrix (1-5). The advantages of enzyme-immobilization were improv...
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