molecular evidence on the heterogeneity present in the ole e 1 allergen of the olive pollen is emerging. such polymorphism is dependent on the cultivar origin of pollen, which also determines wide differences in the expression of this protein. determination of biochemical and molecular characteristics of ole e 1 pollen allergen in two iranian olive cultivars, namely 'rowghani' and 'zard' is nec...

during past few years, the cupressus arizonica has been abundantly planted in tehran, causing a significant increase of allergic diseases from the middle of winter to the beginning of spring. the aim of this study was the comparison of pollen protein content in two major varieties of c. arizonica planted in tehran, including c. arizonica var. arizonica and c. arizonica var. glabra , in order to...

OBJECTIVE Allergic rhinitis and allergic asthma are important chronic diseases posing serious public health issues in Australia with associated medical, economic, and societal burdens. Pollen are significant sources of clinically relevant outdoor aeroallergens, recognised as both a major trigger for, and cause of, allergic respiratory diseases. This study aimed to provide a national, and indeed...

Summary Different phenotypes of allergic rhinitis have been identified based on the seasonality of the allergen involved. Within pollinosis, importance has to be paid to the responsible pollen species. Guidelines for clinical management are mostly based on studies performed in patients with grass pollen allergy. Only few data is available on tree pollen allergy and more specifically on cypress ...

Pollen allergies have been rapidly increasing over the last decades. Many allergenic proteins and non-allergenic adjuvant compounds of pollen are involved in the plant defense against environmental or microbial stress. The first aim of this study was to analyze and compare the colonizing microbes on allergenic pollen. The second aim was to investigate detectable correlations between pollen micr...

BACKGROUND The work- or environmental-related type I sensitization to maize pollen is hardly investigated. We sought to determine the prevalence of sensitization to maize pollen among exposed workers and to identify the eliciting allergens. METHODS In July 2010, 8 out of 11 subjects were examined who were repeatedly exposed to maize pollen by pollinating maize during their work in a biologica...

BACKGROUND Maize is a member of the Poaceae family, capable of producing large amounts of pollen grains which may constitute important allergens in spring and summer. The aim of this study was to determine the protein content of maize pollen and its allergenicity in guinea pigs. METHODS The morphology of maize pollens was determined using light microscopy and scanning electron microscopy. The...

The structure of an allergen plays a crucial role in type I allergy. It is involved in the sensitization process as well as in allergic reactions that are caused by repetitive exposure. Here, we focused on the abundant group I allergens of grass pollen, which are known for their IgE inducing potential. We identified at least four independent IgE-binding regions (conformational epitopes) on the ...

UNLABELLED BACKGROUND Grass pollen is a major cause of respiratory allergy worldwide and contain a number of allergens, some of theme (Phl p 1, Phl p 2, Phl p 5, and Phl 6 from Phleum pratense, and their homologous in other grasses) are known as major allergens. The administration of grass pollen extracts by immunotherapy generally induces an initial rise in specific immunoglobulin E (sIgE) ...

INTRODUCTION The objective of this study was to compare the efficacy and safety of olopatadine versus epinastine in healthy Japanese adults with a history of allergic conjunctivitis to Japanese cedar pollen. METHODS This Phase IV double-blind randomized controlled clinical trial comprised three clinical visits over 30 days. Screening tests were performed to identify subjects with a history of...