Background. Preoperative fasting (POF) is physiologically and precautionary important during anesthesia and surgery. POF from midnight has been practiced despite the recommended shorter practice. Objective. Assessing preoperative fasting among adult patients scheduled for elective surgery at Kenyatta National Hospital (KNH). Methods. A descriptive cross-sectional study involving 65 surgical pat...

Inhibin is an important glycoprotein that is involved in folliculogenesis. INHA, the gene encoding the inhibin alpha subunit, was recently proposed as a candidate for premature ovarian failure (POF), a syndrome that leads to the cessation of ovarian function under the age of 40 years. 70 POF patients and 70 controls were screened for the previously identified INHA -16C>T transition mutation. Th...

Background: Premature Ovarian Failure (POF) is a life-changing condition that affects 1% of women under the age of 40. POF is also known as premature menopause, and hyper gonadotropic hypogonadism; POF can be primary (spontaneous) or secondary which is usually induced by radiation, chemotherapy or surgery. It comprises of amenorrhea, high menopausal levels of gonadotropin and sex steroid defici...

Polymer optical fiber (POF) sensors based on the Optical Time Domain Reflectometry (OTDR) technique provide the unique ability to measure high strain up to 40 % fully distributed along the fiber. Standard PMMA POF are introduced and evaluated in potential use and applicability. The advances in distributed POF strain sensor technology are concluded with respect to application in structural healt...

The practical use of multiobjective optimization tools in industry is still an open issue. A strategy for reduction of objective function calls is often essential, at a fixed degree of Pareto Optimal Front (POF) approximation accuracy . To this aim an extension of single-objective NN-based GRS methods to Pareto Optimal Front (POF) approximation is proposed. Such an extension is not at all strai...

Premature ovarian failure (POF) is the term usually used to describe women aged younger than 40 years, who present with amenorrhoea, hypergonadotropic hypogonadism, and infertility. POF is a devastating diagnosis for reproductive-aged women. The clinical presentation is diverse, and several different disorders can lead to premature ovarian failure. POF has serious health consequences, including...

Two completely different approaches for a Gigabit Ethernet compliant stream transmission over 50m of 1mm PMMA SI-POF have been experimentally demonstrated and are compared in this paper. The first solution is based on a commercial RC-LED transmission and a careful optimization of the physical layer architecture, realized during the POF-PLUS EU Project. The second solution exploits the performan...

Recent reports suggest that women with FRAXA premutations have an increased likelihood of having premature ovarian failure (POF). We screened 147 women with idiopathic POF for the number of trinucleotide repeats at the FRAXA and FRAXE loci. We found six women with FRAXA premutations, including four familial and two sporadic cases, but no women with FRAXA full mutations. At the FRAXE locus there...

In this work we present a high-speed optical receiver with external large-area photodiode. The optical receiver is realized in 0.35μm SiGe BiCMOS technology. The input circuit is a two-transistor transimpedance amplifier using an common-emitter and an emitter-follower configuration. An external silicon PIN photodiode of a squared area of 0.25mm2 with a rise time of 0.4ns at 850nm light is used....

Premature Ovarian Failure (POF) is associated with subfertility. Despite efforts to induce ovulation, success rates are low. We report a case of POF spontaneously conceiving twins while on hormone replacement therapy.