BACKGROUND Polymerase chain reaction (PCR) is a molecular biology technique which can detect Mycobacterium tuberculosis (TB) genome in pleural fluid; however, the results are variable. METHODS Two hundred and twelve pleural fluid specimens suspected to be possibly associated with tuberculosis with negative acid-fast smears were sent to our laboratory to test for the presence of M. tuberculosi...

Over the past 15 years, resection phthisiosurgery has gained recognition and is widely used in complex treatment of pulmonary tuberculosis. However, with lung resection, various complications occur postoperative long-term period. Of these, most dangerous severe are pleural empyema, bronchial fistulas, exacerbations relapses tuberculosis process. According to domestic foreign authors, frequency ...

OBJECTIVE To evaluate in chest X-rays and high-resolution computed tomographies of patients with pleural tuberculosis, the incidence of parenchymal and mediastinal lung lesions suggestive of active disease. METHODS Prospective study (2008-2009) evaluating the radiographic and tomographic abnormalities of 88 HIV-negative patients with pleural tuberculosis (unilateral effusion). The images were...

The aim of this study was to evaluate the efficacy of combination of adenosine deaminase and polymerase chain reaction in the diagnosis of tubercular effusions. This study was conducted in the department of General Medicine and Cardiovascular and thoracic surgery SKIMS for a period of two years between November 2008 to November 2010. A total of 57 patients presenting with pleural effusion durin...

We prospectively compared the culture yields of two pleural fluid volumes (5 and 100 ml) inoculated in liquid culture medium in 77 patients of whom 58 (75.3%) were diagnosed with pleural tuberculosis. The overall fluid culture yield was high (60.3% of cases with pleural tuberculosis). The larger volume had a faster time to positivity (329 vs 376 h, p=0.055) but its yield was not significantly h...

A 77-year-old Haitian woman complained of two months history of cough and left upper quadrant abdominal pain. She had a remote history of tuberculosis that was treated back in Haiti many years ago. Imaging studies showed a left pleural effusion with posterior pleural thickening as well as lymphadenopathy in the left hilum and left supraclavicular area. The Pleural biopsy was consistent with ext...

Fibronectin is a glycoprotein found in body fluids, loose connective tissue matrix and in basement membranes. Fibronectin in pleural effusion was found to be immunologically indistinguishable from the plasma form, as shown by double-diffusion analysis. Fibronectin isolated from pleural fluid by affinity chromatography on gelatin-Sepharose had a polypeptide pattern similar to that of plasma fibr...

The specificities and sensitivities of the Bactec mycobacterial growth indicator tube (MGIT) system for the recovery of Mycobacterium tuberculosis from pleural fluid are not statistically different than those of the Myco/F lytic liquid culture system. The time to positivity is shorter in the MGIT system (12.7 versus 20.7 days, respectively; P=0.007). The Myco/F lytic culture system may be an al...

Tuberculosis is one of the most prevalent disease developing countries resulting in significant morbidity. Extra pulmonary tuberculosis results pleurisy among predilection to other organ and systems like lymph nodes. Pleurisy tubercular pleural effusion. Pleural effusions are mostly seen immunocompetent patients. Here we present a case effusion which was diagnosed by cytology examination fluid ...

Tuberculous (TB) pleural effusion occurs in approximately 5% of patients with Mycobacterium tuberculosis infection. The HIV pandemic has been associated with a doubling of the incidence of extrapulmonary TB, which has resulted in increased recognition of TB pleural effusions even in developed nations. Recent studies have provided insights into the immunopathogenesis of pleural TB, including mem...