نتایج جستجو برای: plasminogen activator inhibitor 1
تعداد نتایج: 2909706 فیلتر نتایج به سال:
The secretion of tissue plasminogen activator ft-PA). urokinase (u-PA) and their inhibitors by the human leukemia cell line K562 was examined. K562 cells normally secrete both t -PA and u-PA in a ratio of 3:1 . After addition of 10 or 1 ng/mL phorbol myristate acetate (PMA) to K562 cells. a marked decrease in enzymatic activity is observed in the medium. However. when t-PA antigen rather than a...
Coagulopathy is a well recognised complication of peritoneovenous shunting for ascites. The relative contributions of primary fibrinolysis and disseminated intravascular coagulation remain controversial. Plasminogen activating activity was significantly lower in malignant ascites (n = 10, median < 0.02 (range < 0.02-1.26) IU/ml) than in alcoholic ascites (n = 10, 1.07 (0.30-1.49) IU/ml) (p < 0....
BACKGROUND The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control. OBJECTIVES The study aimed to test if in vivo pharmacological intervention by valproic acid treatment would lead to increase in tissue plasminogen activator release capacity. METHODS In an anaesthetized pig model, a controlle...
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