Objectives We set out to investigate the prevalence, different mechanisms, and clonal relatedness of multidrug resistance (MDR) among third-generation cephalosporin-resistant Gram-negative clinical isolates from Egypt. Materials and methods A total of 118 third-generation cephalosporin-resistant Gram-negative clinical isolates were included in this study. Their antimicrobial susceptibility pa...

Objectives: To establish the in vitro susceptibility of gonococci isolated in the London area to antibiotics in current therapeutic use and to establish a sentinel surveillance system for monitoring trends in antibiotic resistant gonorrhoea in London. Methods: Isolates of Neisseria gonorrhoeae from consecutive patients attending genitourinary medicine clinics at 10 hospitals in the London area ...

INTRODUCTION At the time of the study, 3 plasmid-borne qnr determinants (qnrA, qnrB and qnrS) and 1 plasmid-borne aminoglycoside-modifying enzyme determinant that confers quinolone resistance (aac(6')-Ib-cr) had been described in the literature. MATERIALS AND METHODS We studied the prevalence of the 3 qnr determinants in a total of 117 nalidixic acid-resistant urinary isolates of Klebsiella p...

OBJECTIVES To establish the in vitro susceptibility of gonococci isolated in the London area to antibiotics in current therapeutic use and to establish a sentinel surveillance system for monitoring trends in antibiotic resistant gonorrhoea in London. METHODS Isolates of Neisseria gonorrhoeae from consecutive patients attending genitourinary medicine clinics at 10 hospitals in the London area ...

The dissemination of plasmid-mediated antimicrobial resistance genes may pose a substantial public health risk. In the present work, the occurrences of blaCTX-M and plasmid-mediated ampC and qnr genes were investigated in Escherichia coli from 16 chicken carcasses produced by four commercial brands in Brazil. Of the brands tested, three were exporters, including one of organic chicken. Our stud...

background : plasmid mediated quinolone resistance (pmqr) has been shown to play an important role in resistance not only to quinolones, but also β-lactams and aminoglycosides. in fact, qnr genes are frequently carried along with β-lactamase determinants on the same plasmids. we studied the prevalence of qnra , qnrb , qnrs and aac(6’)-ib-cr genes among quinolone and cephalosporin resistant clin...

The mcr-1 gene mediating mobile colistin resistance in Escherichia coli was first reported China 2016 followed by reports among different species worldwide, especially E. and Klebsiella . However, data on its transmission Salmonella are still lacking. This study analyzed the antimicrobial (AMR) profiles presence 755 foodborne from 26 provinces of mainland, 2016. Genomic features two mcr-1- carr...