The neuropeptide Oxytocin influences a number of social behaviors, including processing of faces. We examined whether Oxytocin facilitates the processing of out-group faces and reduce the own-race bias (ORB). The ORB is a robust phenomenon characterized by poor recognition memory of other-race faces compared to same-race faces. In Experiment 1, participants received intranasal solutions of Oxyt...

OBJECTIVE Impaired insulin-mediated hepatic glucose uptake (HGU) has been implicated in the hyperglycemia of type 2 diabetes. We examined the effects of metformin (2 g/day) and rosiglitazone (8 mg/day) monotherapy on HGU and its relation to subcutaneous fat, visceral fat (VF), and whole-body insulin-mediated glucose metabolism in type 2 diabetic patients. RESEARCH DESIGN AND METHODS Glucose u...

conclusions eps 7630 was found to be efficacious in the treatment of acute tonsillopharyngitis in children and was very well tolerated. methods in this double-blind placebo-controlled clinical trial with a group sequential design, the efficacy and tolerability of eps 7630 were investigated in 6- to 10-year-old patients with acute tonsillopharyngitis, who showed no evidence of group a β-hemolyti...

Osimertinib is a third-generation, irreversible, oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that potently and selectively inhibits EGFR TKI-sensitizing T790M resistance mutations with demonstrated efficacy in EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC), including central nervous system (CNS) metastases. the preferred first-line treatment EGFRm advance...

BACKGROUND Increases in measles antibodies without rash-illnesses have been documented in previously vaccinated children exposed to measles cases. The phenomenon has been incompletely evaluated in young unvaccinated infants with immunity of maternal origin. METHODS Monthly cohorts of newborns were prospectively randomized to vaccine and placebo control groups during a trial of high-titre vacc...

OBJECTIVE To investigate digital microvascular responses to topical glyceryl trinitrate (GTN) in patients with primary Raynaud's phenomenon (PRP), limited cutaneous systemic sclerosis (LCSSc) and healthy control subjects, using laser Doppler imaging. METHODS Ten patients with PRP, 13 with LCSSc and 10 control subjects were studied. Baseline skin microvascular blood flow of the dorsum of the i...