Abstract. A case of a female, 10-year-old rhesus macaque (Macaca mulatta) with spontaneous chronic lymphocytic thyroiditis is presented. At necropsy, the thyroid gland was slightly enlarged, up to 2 mm large, round, confluent, beige foci on surface both lobes. Histopathologic features resembled human Hashimoto's thyroiditis: multifocally, interstitium infiltrated by lymphocytes and variably siz...

In tropical countries such as India, it has been observed that a number of buffalo cows experience seasonal anestrous during summer months. This might be due to seasonal changes in responsiveness of pituitary gland to gonadotropin releasing hormone (GnRH) and/or decreased hypothalamic GnRH release. Attempts were made to characterize the responsiveness of pituitary gland to a range of doses (0.1...

Autoimmune lymphocytic infiltration of the pituitary gland is rare. In the five previously reported cases [1-5], there was c linical evidence of hypopituitarism but the diagnosis of lymphocytic adenohypophysitis was made only by postmortem examination of the pituitary gland . I describe a case of lymphocytic adenohypophysitis in a young , multiparous woman who had clinical features of a prolact...

Hormones secreted from the pituitary gland regulate important processes such as development, growth and metabolism, reproduction, water balance, and body pigmentation. Synthesis and secretion of pituitary hormones are regulated by different factors from the hypothalamus, but also through feedback mechanisms from peripheral organs, and from the pituitary itself. In the European eel extensive att...

To a great extent, animal growth is regulated by the pituitary gland and its secretions of growth hormone (somatotropin). Implants work by increasing (via the pituitary gland) growth hormone and insulin at the cellular level, which results in increased synthesis of muscle tissue and, frequently, reduced deposition of body fat. This causes a measurable increase in growth rate and improved feed e...

Ag expressed exclusively in the anterior pituitary gland and secreted locally by pituitary somatotrophs can gain access to the MHC class I presentation pathway and activate CD8 T cells. Influenza nucleoprotein (NP) was expressed as a transgene under the control of the human growth hormone (GH) locus control region. Activation of monoclonal F5 CD8 T cells specific for NP resulted in spontaneous ...

BACKGROUND AND PURPOSE A thorough knowledge of fetal growth and development is key to understanding both the normal and abnormal fetal MR imaging findings. We investigated the size and signal intensity of the normal pituitary gland and the intrasphenoidal ossification around the Rathke pouch in formalin-fixed fetuses on MR imaging. MATERIALS AND METHODS Thirty-two fetuses with undamaged brain...

A woman with sarcoidosis and primary hypothyroidism presented with partial hypopituitarism without pituitary gland enlargement. A clinical diagnosis of lymphocytic hypophysitis was established after exclusion of other possibilities, since a definitive diagnosis can only be made after histological studies. This rare form of chronic inflammation and destruction of the anterior pituitary gland is ...