Paired immunoglobulin-like receptor B (PIR-B) partially mediates the regeneration-inhibiting effects of the myelin-derived protein Nogo, myelin-associated glycoprotein (MAG), and oligodendrocyte-myelin glycoprotein (OMgp). In this study, we report that inhibition of the PIR-B signaling cascades in neurons enhances axon regeneration in the central nervous system (CNS). Binding of MAG to PIR-B le...

The aim of this study was to establish how a membrane property contributes to the neuronal discharge during ongoing behavior. We therefore studied the role of the postinhibitory rebound (PIR) in the bursting discharge of lumbar motoneurons intracellularly recorded in newborn rat in vitro brain stem/spinal cord preparation. The PIR is a transient depolarization that occurs after a hyperpolarizat...

BACKGROUND Circulating microRNAs are potential markers for disease detection. A novel class of small non-coding RNAs called Piwi-interacting RNAs (piRNAs) has been recently reported to participate in the epigenetic regulation of cancers and other diseases. This study aims to discover blood-based piRNAs which can be used as markers for disease detection and monitoring. MATERIALS AND METHODS We...

Private Information Retrieval (PIR) protects users’ privacy in outsourced storage applications and can be achieved using additively homomorphic encryption schemes. Several PIR schemes with a “real world” level of practicality, both in terms of computational and communication complexity, have been recently studied and implemented. One of the possible building block is a conceptually simple and c...

PiwiRNAs, small non-coding RNAs processed by Piwi proteins, are involved in maintaining genome stability in germline cells. Recently, piwiRNA expression has been identified in some tumors. We have examined the potential reactivation of the Piwi/piwiRNA pathway in classical Hodgkin lymphoma (cHL). We found that Piwi proteins and three selected piwiRNAs, including piR-651, were expressed in cHL p...

The problem of private information retrieval with private side information (PIR-PSI) is recently introduced by Kadhe et al. In this problem, N replicated databases each store K messages, of which M are known to the user as side-information. The identity of these M messages is unknown to the databases. The user wishes to retrieve, as efficiently as possible, a new desired message without reveali...

Private Information Retrieval (PIR) protocols aim at ensuring a user that he can retrieve some part Di of a distributed database D without revealing the index i to the server(s). Most of known PIR protocols focus on decreasing the communication complexity between the client and the server(s). Recently, the use of PIR codes by Fazeli et. al. also lead to a huge reduction of the storage overhead ...

Although Sufi-led political parties have been active in Bangladesh for almost four decades, they received little scholarly attention. Therefore, this article discusses the historical context within which post-independence Sufi/Pir-centred emerged, their interaction with other parties, and electoral performance. It also touches upon some basic issues relating to Pir-cum leaders: once a Pir becom...