Density functional theory (DFT) was utilized to investigate the hydrolysis reaction mechanisms of phosphodiester BNPP (BNPP = bis(4-nitrophenyl)phosphate) catalyzed by a symmetrical oxyimine-based macrocyclic dinuclear zinc(ii) complex. We examined the nature of the nucleophilic reagent and the active form of the catalyst. The coordination and binding models of the catalyst-substrate complex we...

To simplify the programming of hierarchical and distributed-memory parallel systems, the notion of shared virtual memory (SVM) has been proposed. This abstraction provides the programmer with the illusion of a at global address space and coherence is maintained at the page level. The success of this abstraction depends on the eeciency of page management. This in turn depends on the eeciency of ...

A set of small RNAs known as rasRNAs (repeat-associated small RNAs) have been related to the down-regulation of Transposable Elements (TEs) to safeguard genome integrity. Two key members of the rasRNAs group are piRNAs and endo-siRNAs. We have performed a comparative analysis of piRNAs and endo-siRNAs present in mouse oocytes, spermatozoa and zygotes, identified by deep sequencing and bioinform...

Sec Delta (ms) Figure 7: Optimal values of. Left: Execution time of FS-TSP for k = 2; Optimal value of is 150ms. Right: Execution time of FS-TSP for k = 3; Optimal value is 300ms. a mechanism that will optimize the migration decisions in a distributed environment supporting object oriented programming and concurrent execution. There are many apparent directions that are yet to be explored. In p...

Consider the class of protocols, for two participants, in which the initiator applies a sequence of operators to a message M and sends it to the other participant ; in each step, one of the participants applies a sequence of operators to the message received last, and sends it back . This "ping-pong" action continues several times, using sequences of operators as specified by the protocol . The...