There is a widespread agreement that more effective drug delivery vehicles with more alternatives, as well as better active pharmaceutical ingredients (APIs), must be developed to improve the efficacy of microbicide products. For instance, in tropical regions, films are more appropriate than gels due to better stability of drugs at extremes of moisture and temperature. Here, we apply fundamenta...

Protein remote homology detection is one of the most important problems in bioinformatics. Discriminative methods such as support vector machines (SVM) have shown superior performance. However, the performance of SVM-based methods depends on the vector representations of the protein sequences. Prior works have demonstrated that sequence-order effects are relevant for discrimination, but little ...

Study Design: Prospective, randomized, crossover design. Objectives: To compare the effectiveness of the Johnson & Johnson Back Plaster, the ABC Warme-Pflaster, and the ThermaCare HeatWrap on skin and paraspinal muscle temperature. Also, to compare the subjects’ heat perception for the 3 products. Background: Heat therapy is a common treatment for low back pain and disability. There are a numbe...

Study Design: Clinical case report. Objectives: To describe a physical therapy program addressing impairments of the upper thoracic and cervical spine region for an individual with a whiplash-associated disorder. Background: A 32-year-old female with complaint of diffuse posterior cervical and upper thoracic region pain was evaluated 2 weeks following a motor vehicle accident. The patient repor...

Study Design: Case control group study. Objectives: To compare scapular position and orientation between baseball players with and without pathologic internal impingement. Background: Scapular dysfunction has been implicated as a contributor to throwing-related pathologic internal impingement of the shoulder due to its role in increasing the contact between the greater tuberosity and posterior-...

Study Design: Prospective nonrandomized controlled trial. Objectives: To determine the effect of fibular repositioning tape (FRT) on incidence and severity of ankle injury. Background: Pain and functional disability is common following ankle sprain and a major problem in sport. A novel method of taping, FRT, which has been described to prevent ankle sprain, requires less tape than traditional m...

Background: There are few epidemiological reports on adherence to physical activity (PA) and screen-time (ST) recommendations among Iranian children and adolescents at the provincial level. We used nationally representative data to provide recent prevalence estimates of Iranian children who met the recommendations for PA and ST.   Methods: This nationwide study was conducted among 14,88...

Regular physical activity (PA) is one of the most effective recommendations to prevent diabetic complications. However, the reported level of PA is low in this group. This study evaluates intervention based on the implementation intention (II) theory, to improve the level of PA and the health of patients with diabetes. Materials and Methods: This randomized control study was conducted on 124 p...

Study Design: Repeated-measures experimental design. Objective: To determine the effects of shoulder external rotator muscle fatigue on 3-dimensional scapulothoracic and glenohumeral kinematics. Background: The external rotator muscles of the shoulder are important for normal shoulder function. Impaired performance of these muscles has been observed in subjects with impingement syndrome and it ...

Design: Retrospective ex-post facto design. Objectives: To retrospectively review the management of patients with lateral epicondylalgia, and to compare self-reported outcomes to assess the potential benefit of manual physical therapy to the cervical spine. Background: It has been postulated that dysfunction of the cervical spine may contribute to the symptoms associated with lateral epicondyla...