We present a new probabilistic model of evolution of RNA-, DNA-, or protein-like sequences and a tool rose that implements this model. By insertion, deletion and substitution of characters, a family of sequences is created from a common ancestor. During this artificial evolutionary process, the ’~true" history is logged and the "correct" multiple sequence alignment is ereated simultaneously. We...

The phylogenic and ontogenic expression of mRNA for the Na+/bile acid cotransporter was determined by Northern analysis utilizing a full-length cDNA probe recently cloned from rat liver. mRNA was detected in several mammalian species, including rat, mouse, and man, but could not be found in livers from nonmammalian species, including chicken, turtle, frog, and small skate. When expression of th...

Abstract Background Rose ( Rosa chinensis ) is a traditional famous flower with valuable ornamental characteristics. However, drought stress restricts its growth and development, leading to an abnormal phenotype. One of the main transcription factor (TF) protein groups in plant kingdom are APETALA2/ethylene-responsive (AP2/ERF) proteins potentially involved responses various plants. Results Our...

Introduction: Newcastle Disease (ND) is an infectious disease in various types of poultry caused by the Virus (NDV). Cases ND Indonesia have been reported commercial and backyard chickens, pigeons, ducks geese, even eagles peacocks. Peacock a wild bird protected Indonesia's Government Regulation No. 7 1999. This study aims to identify, isolate characterize NDV molecularly cases diagnosed as Met...

Coffee leaf rust (CLR), caused by Hemileiavastatrixis the main coffee disease, occurring in producing countries worldwide. Effective management of CL Rintegrated approch including development resistant varieties, cultural management, biocontrol and chemicals. Considering both potential source bioagents this ecological niche possibility practical uses as a tool to be deployed against rust. White...

Caragana korshinskii Kom. is widely distributed in various habitats, including gravel desert, clay desert, fixed and semi-fixed sand, and saline land in the Asian and African deserts. To date, no previous genomic information or EST-SSR marker has been reported in Caragana Fabr. genus. In this study, more than two billion bases of high-quality sequence of C. korshinskii were generated by using i...

BACKGROUND Exploring the rate of naturally occurring NS3 protease mutants in HCV infected population is influential in the future therapeutic approaches. OBJECTIVES This study explored naturally occurring resistant mutations to protease inhibitors in a pilot study. PATIENTS AND METHODS We analyzed NS3 gene sequences in 7 HCV infected patients, referred to the central liver center, south of ...

BACKGROUND The occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the sera or in the liver biopsy and the absence of hepatitis B surface antigen (HBsAg) by serological test. OBJECTIVES The current study aimed to evaluate the occult HBV infection by polymerase chain reaction (PCR) and determine HBV genotyping among the patients with abnormal alanine...