background: phototherapy is believed to be a safe method for the management of hyperbilirubinemia. however, there are some controversial issues regarding the genotoxic effects of phototherapy on dna. the aim of this study was to investigate morphologically both phototherapy-induced dna double-strand breaks (dsbs) and apoptosis in lymphocytes derived from jaundiced and non-jaundiced neonates. me...

BACKGROUND Phototherapy is considered the standard of care for neonatal jaundice. However, its short-term cardiorespiratory effects have not been studied thoroughly. OBJECTIVES To assess the cardiorespiratory effect of phototherapy during sleep in term infants with physiologicjaundice. METHODS We performed two polysomnography studies during 3 hours sleep in 10 healthy term infants with phys...

A citretin plus UV-B phototherapy is a highly effective and relatively safe treatment for psoriasis, limited by the inconvenience and cost of office-based treatment. Home phototherapy offers greater convenience, but the safety and efficacy of its use outside the physician’s office has not been well studied. The purpose of this study is to provide a preliminary assessment of home-based narrowban...

background : vitiligo is an acquired disease of skin that presents with depigmented patches due to lack of melanocytes in the epidermis. accumulation of toxic free radicals like hydrogen peroxide in the epidermis may be responsible for melanocytes death. since ethyl vanillate (vanillic acid ethyl ester) is a strong hydrogen peroxide scavenger, it may be effective against vitiligo. this study wa...

Bakground: Phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia as well as the management of subsequent complications in the newborn.  However, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. Objective: This study was under-taken to investigate photo...

Background: There might be a close link between neonatal icterus and/or neonatal phototherapy and childhood asthma. The present study aimed to assess the relationship between neonatal icterus and/or phototherapy and the likelihood of childhood asthma among Iranian population. Materials and Methods The present case-control study was performed on 102 consecutive asthmatic children hospitalized at...

backgroundmany studies reported that copper, zinc and magnesium play important roles in the pathogenesis and development of neonatal hyperbilirubinemia. exchange transfusion and intensive phototherapy are known two modalities of therapy for severe neonatal hyper bilirubinemia, but the effect of them on those trace elements is unknown.materials and methodscopper, zinc and magnesium serum levels ...

conclusions according to our study, phototherapy should not be used as prophylactic therapy for all vlbw infants, but rather it should be individualized in order to maintain low bilirubin levels. results the mean bilirubin level on the first day in both groups exhibited no significant difference. the peak serum bilirubin was 7.7 ± 1.4 and 8.5 ± 2.1 mg/dl in the prophylactic and therapeutic grou...

The objective of this study was to investigate the effect of intranasal phototherapy on nasal microbial flora in patients with allergic rhinitis. This prospective, self-comparised, single blind study was performed on patients with a history of at least two years of moderate-to-severe perennial allergic rhinitis that was not controlled by anti-allergic drugs. Thirty-one perennial allergic rhinit...

BACKGROUND Ultraviolet A1 (340-400 nm, UVA1) phototherapy is highly effective in sclerotic lesions of systemic sclerosis (SSc). Histological evaluation of skin specimens obtained before and after UVA1 phototherapy revealed loosening of collagen bundles and the appearance of small collagen fibers. We have previously shown that UVA1 irradiation induced collagenase in vitro study by using SSc fibr...