Patient acceptability of a medicinal product is a key aspect in the development and prescribing of medicines. Children and older adults differ in many aspects from the other age subsets of population and require particular considerations in medication acceptability. This review highlights the similarities and differences in these two age groups in relation to factors affecting acceptability of ...

There is no approved comparator list in Mongolia. The innovator pharmaceutical product is usually the most logical comparator product for a multisource pharmaceutical product because its quality, safety and efficacy should have been well assessed and documented in premarketing studies and postmarketing monitoring schemes. There are registered 65 products in Mongolia, containing Paracetamol, and...

BACKGROUND A lack of age-appropriate formulations can make it difficult to administer medicines to children. A manipulation of the dosage form may be required to achieve the required dose. This study aimed to describe medicines that are manipulated to achieve the required dose in paediatric practice. METHOD A structured, undisguised observational study and postal survey. The observational stu...

This paper explains the history, the idea as well as usages and problems of traditional IP multicast. Furthermore, in this paper I discuss the very recent idea of IP multicast, FRM (Free Riding Multicast), which has been suggested in 2006.

The WHO biowaiver procedure for BCS Class II weak acids was evaluated by running two multisource IR ibuprofen drug products (Ibuprofen, 200 mg tablets, Tatchempharmpreparaty, Russia and Ibuprofen, 200 mg tablets, Biosintez, Russia) with current Marketing Authorizations (i.e. in vivo bioequivalent) through that procedure. Risks associated with excipients interaction and therapeutic index were co...

Polymers are tools used in novel drug delivery system to modify the drug release of pharmaceutical dosage form. Polyox is hydrophilic polymer made of non-ionic homopolymer of ethylene oxide. Polyox is popular for its film forming, binding, lubricating, mucoadhesive, viscosity imparting property in pharmaceuticals. Polyox are available in various grades based on its molecular weight. Lower molec...

A simple, selective, precise and accurate Reverse Phase High Pressure LiquidChromatographic (RPHPLC) method was developed and validated for the simultaneousestimation ofgatifloxacin and difluprednate in pharmaceutical dosage forms.The method was validated for accuracy, specificity, linearity and robustness asper the ICH guidelines.Binary elution at a flow rate of 1.0 mL per min was employed onE...