UNLABELLED Precise assessment of lymph node metastases is critical to the treatment outcome and overall survival of patients with head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to investigate the effect of time-of-flight (TOF) technique on the diagnostic performance of (18)F-FDG PET/CT for assessment of lymph node metastases in HNSCC patients. METHODS In 39 patie...

In this paper, we explore the PET-MRI 3D surface image registration method for the longitudinal study of cancer. Image registration gives new information to the radiologists by matching images with different modalities. The objective of this research is to develop 3D surface registration for PET/CT and MR images acquired by different medical imaging systems at different times. Our proposed meth...

Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results ...

In this paper we present illustrative visualization techniques for PET/CT datasets. PET/CT scanners acquire both PET and CT image data in order to combine functional metabolic information with structural anatomical information. Current visualization techniques mainly rely on 2D image fusion techniques to convey this combined information to physicians. We introduce an illustrative 3D visualizati...

Positron Emission Tomography (PET) is a nuclear medicine imaging technique that is widely used in early detection and treatment follow up of many diseases, including cancer. This modality requires positron-emitting isotope labeled biomolecules, which are synthesized prior to perform imaging studies. Fluorine-18 is one of the several isotopes of fluorine that is routinely used in radiolabeling o...

UNLABELLED Registration and fusion of whole-body functional PET and anatomic CT is significant for accurate differentiation of viable tumors from benign masses, radiotherapy planning and monitoring treatment response, and cancer staging. Whole-body PET and CT acquired on separate scanners are misregistered because of differences in patient positions and orientations, couch shapes, and breathing...