نتایج جستجو برای: peroxisome biogenesis
تعداد نتایج: 36041 فیلتر نتایج به سال:
1 1 Short title: Update on plant peroxisomes 2 3 Corresponding author: Bonnie Bartel, Rice University, MS-140, 6100 Main Street, 4 Houston, Texas 77005; Phone: 713-348-5602; E-mail: [email protected] 5 6 7 Peroxisome function, biogenesis, and dynamics in plants 8 9 Yun-Ting Kao2, Kim L. Gonzalez2, and Bonnie Bartel* 10 11 Department of Biosciences, Rice University, Houston Texas 77005 12 13 ORCID...
Pex3p and Pex19p are key players in the post-translational import of peroxisomal membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a cytosolic chaperone and import receptor for peroxisomal membrane proteins, and Pex3p as docking factor at the peroxisomal membrane.
Peroxisomes are ubiquitous organelles in mammalian cells but it is still unclear how they contribute to normal development and tissue homeostasis. To address this question, gene targeting techniques have been applied on several peroxins to interfere with peroxisome biogenesis in mice. Both peroxins involved in peroxisomal matrix import and peroxins necessary for peroxisome division were inactiv...
PEROXISOMES ARE FORMED BY TWO DISTINCT PATHWAYS the growth and fission of mature peroxisomes and de novo synthesis at the endoplasmic reticulum (ER). While many of the molecular mechanisms underlying these two pathways remain to be elucidated, it is generally accepted that their relative contribution to peroxisome formation may vary depending on the species, cell type and/or physiological statu...
Ben Distel,* Ralf Erdmann, ¢ Stephen J. Gould, ~ Gtinter Blobel,I Denis I. Crane, I James M. Cregg,** Gabriele Dodt,* Yukio Fujiki, *~ Joel M. Goodman, ~ Wilhelm W. Just, D Jan A.K.W. Kiel, 11 Wolf-Hubert Kunau,* Paul B. Lazarow,*** Guy P. Mannaerts, ~*~ Hugo W. Moser, §~§ Takashi Osumi, Richard A. Rachubinski,11~l Adelbert Roscher,**** Suresh Subramani, **¢* Henk F. Tabak,* Toshiro Tsukamoto,l...
Autophagy, an intrinsically nonselective process, can also target selective cargo for degradation. The mechanism of selective peroxisome turnover by autophagy-related processes (pexophagy), termed micropexophagy and macropexophagy, is unknown. We show how a Pichia pastoris protein, PpAtg30, mediates peroxisome selection during pexophagy. It is necessary for pexophagy, but not for other selectiv...
Peroxisomal membrane protein (Pmp)26p (RnPex11p), a major constituent of induced rat liver peroxisomal membrane, was found to contain a COOH-terminal, cytoplasmically exposed consensus dilysine motif with the potential to bind coatomer. Biochemical as well as immunocytochemical evidence is presented showing that peroxisomes incubated with preparations of bovine brain or rat liver cytosol recrui...
In Saccharomyces cerevisiae, peroxisomal inheritance from mother cell to bud is conducted by the class V myosin motor, Myo2p. However, homologues of S. cerevisiae Myo2p peroxisomal receptor, Inp2p, are not readily identifiable outside the Saccharomycetaceae family. Here, we demonstrate an unexpected role for Pex3 proteins in peroxisome inheritance. Both Pex3p and Pex3Bp are peroxisomal integral...
We define the dynamics of spatial and temporal reorganization of the team of proteins and lipids serving peroxisome division. The peroxisome becomes competent for division only after it acquires the complete set of matrix proteins involved in lipid metabolism. Overloading the peroxisome with matrix proteins promotes the relocation of acyl-CoA oxidase (Aox), an enzyme of fatty acid beta-oxidatio...
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