1-Cysteine Peroxiredoxin (1Cys Prx) is a thiol dependent antioxidative enzyme of molecular weight 20-30 kDa. It contains one catalytic cysteine residue and is found in cytosol. Prx plays an important role in growth, development and dessication tolerance in dormant seeds. It detoxifies H2O2 and various other organic peroxides. It protects lipids, enzymes and DNA against reactive oxygen species. ...

The prevalence of cereal allergy is highly influenced by geographical area and consumption habits. According to data from Alergologica 2015 [1], accounts for 2.1% all cases food in Spain. Beer a barley-based alcoholic beverage that also contains hops, yeast, other cereals (wheat, oats, corn, even rye). Barley the basis malt vinegar, whiskey, gin. Several allergens barley have been described, in...

Peroxiredoxins (PRDXs), a ubiquitous family of redox-regulating proteins, are reported of potential to eliminate various reactive oxygen species (ROS). As a major member of the antioxidant enzymes, PRDX1 can become easily over-oxidized on its catalytically active cysteine induced by a variety of stimuli in vitro and in vivo. In nucleus, oligomeric PRDX1 directly associates with p53 or transcrip...

Hydrogen peroxide (H2O2) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors. However, these redox targets are orders of magnitude less H2O2-reactive and abundant than cytoplasmic peroxiredoxins. How can they be oxidized in a signaling time frame? Here we invest...