Galway, Ireland Adipose Derived Stem Cell Transplantation Does Not Improve Recovery of Motor Function after Sciatic Nerve Transaction in Rats D. Angius, A.M. Knight, R.J. Spinner, M.J. Yaszemski, A. J. Windebank. [email protected] 1 Department of Neurosurgery; 2 Department of Neurobiology; 3 Department of Orthopaedics; Mayo Clinic, Rochester USA Introduction In the peripheral nerve sys...

Abstract Introduction Angioleiomyoma is an unusual, benign tumour originating from the tunica media of blood vessels. They commonly occur in face, neck and lower limb. It rarely found hand not considered differential diagnoses painful subcutaneous tumours. Case Report We present a case 40-year-old man with several month history slow growing lump on his right middle finger. He complained pain di...

  Background and Objective: Approximately 45% of benign peripheral nerve sheath tumors (PNST) occur in head and neck regions. Malignant peripheral nerve sheath tumors (MPNST) are less common and only 8-15% of these tumors occur in head and neck region. In this study, we aimed at evaluating the demographic characteristics, pathologic findings, locations, main clinical presentations and family h...

Spinal cord injury elicits an inflammatory response that recruits macrophages to the injured spinal cord. Quantitative real-time PCR results have shown that a repair strategy combining peripheral nerve grafts with acidic fibroblast growth factor (aFGF) induced higher interleukin-4 (IL-4), IL-10, and IL-13 levels in the graft areas of rat spinal cords compared with transected spinal cords at 10 ...

Because there currently is no treatment for spinal cord injury, most patients are living with long-standing injuries. Therefore, strategies aimed at promoting restoration of function to the chronically injured spinal cord have high therapeutic value. For successful regeneration, long-injured axons must overcome their poor intrinsic growth potential as well as the inhibitory environment of the g...

Despite significant advancements in neuroprosthetic control strategies, current peripheral nerve interfacing techniques are limited their ability to facilitate accurate and reliable long-term control. The regenerative interface (RPNI) is a biologically stable bioamplifier of efferent motor action potentials with demonstrated stability. This innovative, straightforward, reproducible surgical tec...

Despite extensive research and surgical innovation, the treatment of peripheral nerve injuries remains a complex issue, particularly in nonsharp lesions. The aim of this study was to assess the clinical outcome in a group of 16 patients who underwent, in emergency, a primary repair for crush injury of sensory and mixed nerves of the upper limb with biological tubulization, namely, the muscle-ve...

Introduction: This project aims to study the regeneration of non-repairable lesions of peripheral nerve by muscle grafts enhanced with growth factors. Material and methods: The experiment was carried out in two phases. The first one compared direct suture of a critical defect in the sciatic nerve of ten rats, with the interposition of autologous muscle graft, denatured by heat, in another ten. ...

Functional recovery after nerve lesions in the peripheral nervous system requires the accurate regeneration of axons to their original target end organs. This paper examines axonal regeneration of the primate median nerve lesioned at the wrist over nerve gap distances of up to 50 mm. Nerve gaps were bridged by either a sural nerve graft or a biodegradable collagen nerve guide tube, and recovery...

abstract introduction & objective: schwannoma, a benign tumor of nerve sheath origin, is commonly found in the head and neck, as well as flexor surfaces of the extremities. it can rarely occur in the breast and stomach with only a few cases being reported. case reports:   the cases are: 1) a 57-year- old man with breast mass, 2) a 58 -year -old man with gastrointestinal complaints who were fina...