BACKGROUND Absolute quantification of perfusion with cardiovascular magnetic resonance has not previously been applied in patients with coronary artery bypass grafting (CABG). Owing to increased contrast bolus dispersion due to the greater distance of travel through a bypass graft, this approach may result in systematic underestimation of myocardial blood flow (MBF). As resting MBF remains norm...

Introduction Accurate measurements of arterial input function (AIF) are indispensable for quantification of perfusion parameters such as MTT, CBV and CBF based on the indicator dilution theory in perfusion imaging using vascular contrast materials. Quantification of cerebral perfusion using deconvolution methods with DSC-MRI has been reported on [1-2]. However, accurately measuring AIF in DSC-M...

BACKGROUND In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before...