نتایج جستجو برای: peptide receptor radionuclide therapy

تعداد نتایج: 1363778  

Journal: :Bioconjugate chemistry 2010
Susan Roosenburg Peter Laverman Lieke Joosten Annemarie Eek Wim J G Oyen Marion de Jong Floris P J T Rutjes Floris L van Delft Otto C Boerman

Radiolabeled cholecystokinin-8 (CCK8) peptide analogues can be used for peptide receptor radionuclide imaging and therapy for tumors expressing CCK2/gastrin receptors. Earlier findings indicated that sulfated CCK8 (sCCK8, Asp-Tyr(OSO(3)H)-Met-Gly-Trp-Met-Asp-Phe-NH(2)) may have better characteristics for peptide receptor radionuclide therapy (PRRT) than gastrin analogues. However, sCCK8 contain...

Journal: :Journal of nuclear medicine technology 2014
Sandip Basu Amit Abhyankar

This report describes a case of extensive diffuse bone marrow involvement with bilateral breast metastases from duodenal neuroendocrine tumor giving rise to a superscan-like appearance on somatostatin receptor-targeted (99m)Tc-hydrazinonicotinamide-TOC scintigraphy. The metastatic lesions demonstrated partial concordance with (18)F-FDG PET/CT findings, signifying varying tumor biology and heter...

2007
Monique de Visser Suzanne M. Verwijnen Marion de Jong

Promotiecommissie Promotoren: Chapter 1 General Introduction: Improvement strategies for peptide receptor scintigraphy and radionuclide therapy. 7 Part I Neurotensin analogs for in vivo targeting of exocrine pancreatic cancer Chapter 2 Stabilised 111 In-labeled DTPA-and DOTA-conjugated neurotensin analogs for imaging and therapy of exocrine pancreatic cancer. 43 Chapter 3 Five stabilized 111 In...

Journal: :Neoplasia 2021

• Molecular response to chemo-, radio- and radionuclide therapy was assessed in NENs. Cisplatin PRRT triggered DNA damage repair-related gene expression. Bortezomib inhibited repair related Combined resulted short-term pro-apoptotic effects vitro . Tumoral heterogeneity interfered with long-term sensitization assessment vivo Background: Well-differentiated gastroenteropancreatic neuroendocrine ...

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