BACKGROUND Peyronie's disease is a relatively common condition in urological practice, but is still poorly identified and understood in the wider medical community and by most of the public. Identifying the condition and appropriate referral for expert opinion can significantly lessen the physical and psychological effect on patients. OBJECTIVE The objective of this article is to provide gene...

Peyronie disease can be physically and psychologically devastating for subjects and their partners. Collagenase Clostridium histolyticum (CCh), a purified mixture of AUX-I and II collagenases, is an intralesional, minimally invasive intervention with evidence of tolerability and efficacy in subjects with PD and is approved by the United States Food and Drug Administration for use in adults who ...

Peyronie disease can be physically and psychologically devastating for subjects and their partners. Collagenase Clostridium histolyticum (CCh), a purified mixture of AUX-I and II collagenases, is an intralesional, minimally invasive intervention with evidence of tolerability and efficacy in subjects with PD and is approved by the United States Food and Drug Administration for use in adults who ...

CONTEXT Peyronie disease (PD) is a connective tissue disorder involving the formation of fibrous plaques in the tunica albuginea. Abnormal plaques and scar tissue create a chronic state of inflammation, causing increased curvature of the penis as well as erectile dysfunction. OBJECTIVE To determine the feasibility and effects of using placental matrix-derived mesenchymal stem cells (PM-MSCs) ...

Penile fracture is a very rare urological emergency resulting from the traumatic rupture of tunica albuginea one or both corpora cavernosa. Immediate surgical treatment current standard care with lower risks late complications, including erectile dysfunction, penile curvature, and tunical scar formation. We report case patient sexual dysfunction who took combination Anafranil Sildenafil to enha...

The objective of this study was to compare the outcomes of the modified Nesbit procedure using different techniques for dissecting the neurovascular bundle (NVB) to correct ventral congenital penile curvatures (CPCs). The bundle was mobilized using the medial and lateral dissection technique in 21 (Group 1) and 13 (Group 2) patients, respectively. In the medial technique, Buck's fascia is opene...

Abstract Introduction Surgical indications for Peyronie's Disease (PD) may constitute severe penile curvature or deformity including unilateral/bilateral corporal indentation/hinging, hour glassing, and concomitant erectile dysfunction. Penile plication, incision/excision of tunical plaques with grafting techniques are widely used. Recently, extratunical has emerged as newer surgical technique ...

Chronic graft versus host disease (GvHD) after allogeneic stem cell transplantation (SCT) may involve any organ system, but male genital involvement is rare. Peyronie's Disease (PD) is an acquired, localized fibrotic disorder of the tunica albuginea, which leads to penile deformity, pain, and eventually to erectile dysfunction. We report the case of a 52 year old African American male with Acut...