psoriasis and pemphigus vulgaris are two inflammatory and autoimmune diseases. their concomitant occurrence in one patient is very rare. we describe a 57-year-old patient with a history of severe plaque type psoriasis for 2 years. after a few months, he presented with disseminated bullae and mucosal erosions which were documented as pemphigus vulgaris. both of the diseases were successfully con...

d-penicillamine is one of the disease-modifying anti-rheumatic drugs (dmards). drug-induced pemphigus is not frequently associated with d-penicillamine, and to date, the number of reported cases is about a hundred. most reports of d-penicillamine-induced pemphigus vulgaris are in patients with rheumatoid arthritis. it has rarely been reported in patients not taking d-penicillamine. we report a ...

background: propranolol has been recently indicated to inhibit the rapid growth and involution of infantile hemangioma. in the present study, we investigated the efficacy and safety of propranolol in iranian infants. methods: a total of 30 infants with indications for medical intervention, such as large hemangiomas, wounds with or without secondary infection, or active trauma-induced bleeding, ...

INTRODUCTION Pemphigus is a rare autoimmune blistering disease, which requires prolonged administration of corticosteroids at high doses. Although this therapy improves the health and lives of patients, it may have various side effects, for example osteoporosis. AIM To assess the concentration of osteoprotegerin (OPG), the soluble receptor activator of nuclear factor-κβ ligand (sRANKL) and os...

Introduction: Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membrane. Antiphospholipid antibodies are a group of autoantibodies found in patients with autoimmune diseases. Due to the risk for thrombotic events in autoimmune diseases, we decided to evaluate the correlation between pemphigus vulgaris and predictive elements of atherothrombosis including antiphospho...

BACKGROUND Pemphigus is a common autoimmune blistering disorder in India. However, there are no population based surveys from India available to study the prevalence of this disease. AIMS To estimate the incidence of pemphigus in Thrissur district, Kerala, South India. METHODS Questionnaire based survey was conducted among the practicing dermatologists of Trichur district between 1 st Janua...

The word “pemphigus” is derived from the Greek term "pemphix” meaning bubble or blister. Pemphigus is a group of autoimmune diseases (see Table 4) characterized by intra-epithelial blistering, resulting in superficial vesicles or bullae that easily rupture, resulting in ulceration of mucosal and/or cutaneous sites. Although rare, pemphigus causes significant morbidity and potential mortality fo...

BACKGROUND Rituximab, a monoclonal anti-CD20 antibody, has been used with encouraging results in pemphigus. We describe herein refractory cases of pemphigus vulgaris (n = 23) and pemphigus foliaceus (n = 1) treated with rituximab in addition to steroids and immunosuppressants. AIMS To assess the response to treatment, the duration of clinical remission, serology of the response and adverse ef...