Forty-two extracts of folk medicinal plant organs from Pakistan were tested in competition binding assays for their interaction with the specific ligand recognition sites on the human alpha2-adrenoceptor subtypes alpha2A, alpha2B and alpha2C Strong binding of the extracts (40 mg/ml) from Acacia nilotica (L.) Delile leaves (88-98% displacement of radiolabel) and Peganum harmala seeds (89-96% dis...

BACKGROUND Leishmaniasis is a major public health problem worldwide. The aim of the present study was to investigate medicinal plants with anti-Leishmania activity which used in Iran. METHODS Data were systematically gathered from five English databases including Ebsco, Science Direct, PubMed, Google Scholar and Scopus, four Persian databases including Magiran, Iran doc, Iran medex and the Sc...

Background: Encounter with drug resistance and replacment natural treatment is essential. From olden of Iran and specially Chaharmahal and bakhtiari Province medicinal smokes such as donkey dung & Peganum harmala seed used for treatment of many diseases like Infectious diseases. Regarded to lake of scientific research about antimicrobial effects of this smoke this study was done with aim of com...

background: sustainable and commercial production of secondary metabolites is a critical issue when dealing with its clinical application. efforts are still being made to look for biotic or abiotic elicitors with more efficient and universal effects on the improvement of secondary metabolites. objective: in order to evaluate the suitability of different biotic elicitors on p. harmala l. cell su...

background:pneumonia and respiratory tract infections, is associated with high mortality and complications in humans. current antibiotics are used to treat this infectious disease, but may lead to many problems such as unwanted side effects and resistance to antibiotics. this study investigated the antibacterial activity of the hydro alcoholic extracts of the native medicinal plants peganum har...

cell cultures of varthemia persica, peganum harmala and pycnocycla spinosa have been studied to evaluate their abilities to bioconvert exogenous hydroquinone. arbutin is an important substance that has several pharmaceutical applications; therefore, we have established v. persica and p. spinosa cultures which seem to be able to metabolize hydroquinone. callus cultures of v. persica were establi...