We demonstrate the de novo fabrication of a biosensor, based upon virus-containing poly(3,4-ethylene-dioxythiophene) (PEDOT) nanowires, that detects prostate-specific membrane antigen (PSMA). This development process occurs in three phases: (1) isolation of a M13 virus with a displayed polypeptide receptor, from a library of ≈10(11) phage-displayed peptides, which binds PSMA with high affinity ...

In this study, poly(3,4-ethylenedioxythiophene)/thiophene-grafted graphene oxide (PEDOT/Th-GO) composites from covalently linking of Th-GO with PEDOT chains were prepared via in situ chemical polymerization with different weight percentage of Th-GO ranging between 40 and 70 % in reaction medium. The resulting composite materials were characterized using a various analytical techniques. The stru...

Poly(3,4-ethylenedioxythiophene) (PEDOT) nanoparticles are loaded with curcumin and piperine by in situ emulsion polymerization using dodecyl benzene sulfonic acid both as a stabilizer and a doping agent. The loaded drugs affect the morphology, size, and colloidal stability of the nanoparticles. Furthermore, kinetics studies of nonstimulated drug release have evidenced that polymer···drug inter...

Electroactive polymer-peptide conjugates have been synthesized by combining poly(3,4-ethylenedioxythiophene), a polythiophene derivative with outstanding properties, and an Arg-Gly-Asp (RGD)-based peptide in which Gly has been replaced by an exotic amino acid bearing a 3,4-ethylenedioxythiophene ring in the side chain. The incorporation of the peptide at the ends of preformed PEDOT chains has b...

The conductivity of a poly(3,4-ethylene dioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) film is enhanced by more than 100-folds on adding some organic compounds into PEDOT:PSS aqueous solutions or by treating the PEDOT:PSS film with organic solvents, such as ethylene glycol (EG), 2-nitroethanol, methyl sulfoxide or 1-methyl-2-pyrrolidinone. The mechanism for this conductivity enhancement wa...

Invited for this issue's Front Cover is the group of Prof. Dr. Tae Hyun Kim from Soonchunhyang University (South Korea). The cover picture illustrates poly(3,4-ethylenedioxythiophene) (PEDOT) electrodeposited thin films (PEDOT-GQD) doped with graphene quantum dots (GQD) as an electrode active material that has a high electrochemically area and interfacial electron transport rate. As result, PED...

Poly(3,4-ethylenedioxythiophene)/zinc oxide (PEDOT/ZnO) nanocomposites were prepared by a simple solid-state heating method, in which the content of ZnO was varied from 10 to 20 wt%. The structure and morphology of the composites were characterized by Fourier transform infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) absorption spectroscopy, X-ray diffraction (XRD), and transmission e...

The synthesis and biomedical applications of nano/micromotors have attracted great attention. In this work, preparation characterization catalytic gold/poly(3,4-ethylenedioxythiophene)/platinum (Au/PEDOT/Pt) micromotors were reported to present their contribution for cancer biomarker miRNA-21 detection. Potential use these motors possible treatment was also illustrated after biocompability had ...

Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is most commonly used as an anode buffer layer in bulk-heterojunction (BHJ) polymer solar cells (PSCs). However, its hygroscopic and acidic nature contributes to the insufficient electrical conductivity, air stability and restricted photovoltaic (PV) performance for the fabricated PSCs. In this study, a new multifunctional add...

Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is an organic mixed ion-electron conducting polymer. The PEDOT phase transports holes and is redox-active, whereas the PSS phase transports ions. When PEDOT is redox-switched between its semiconducting and conducting state, the electronic and optical properties of its bulk are controlled. Therefore, it is appealing to use this t...