We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy (one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four patients. The finding of four affected individuals in three generat...

BACKGROUND Familial hiatal hernia has only rarely been documented. AIMS To describe the pattern of inheritance of familial hiatal hernia within an affected family. SUBJECTS Thirty eight members of a family pedigree across five generations. METHODS All family members were interviewed and investigated by barium meal for evidence of a hiatal hernia. RESULTS Twenty three of 38 family member...

Genetic evaluation based on information from phenotypes, pedigree and markers can be implemented using a recently developed single-step method. In this paper we compare accuracies of predicted breeding values for daily gain and feed conversion ratio (FCR) in Danish Duroc pigs obtained from different versions of single-step methods, the traditional pedigree-based method and the genomic BLUP (GBL...

An unusual pedigree of female-limited seizures with or without mental retardation is updated. The disorder was first detected in a large cohort of women whose fathers were brothers, and affected women had previously transmitted the disorder. Four brothers of affected females have now had five unaffected daughters while four affected women have had four affected and one unaffected daughters and ...

For families, kinship coefficients are quantifications of the amount of genetic sharing between a pair of individuals. These coefficients are critical for understanding the breeding habits and genetic diversity of diploid populations. Historically, computations of the inbreeding coefficient were used to prohibit inbred marriages and prohibit breeding of some pairs of pedigree animals. Such proh...

High-throughput single nucleotide polymorphism genotyping assays conveniently produce genotype data for genome-wide genetic linkage and association studies. For pedigree datasets, the unphased genotype data is used to infer the haplotypes for individuals, according to Mendelian inheritance rules. Linkage studies can then locate putative chromosomal regions based on the haplotype allele sharing ...

Athelia is a rare condition and is almost always associated with other congenital anomalies. There is a heterogeneous pattern of associated clinical features and inheritance concerning this condition. In this case report, we reported a Chinese patient and her father with congenital athelia associated with cleft palate and sparse hair. Pedigree analysis suggests an autosomal dominant inheritance...

A complete family history is critical to the assessment of genetic risk of hereditary diseases. Kinsys0 is a family history-tracking program used by genetic counselors and healthcare professionals for risk assessment. A pedigree, which is a graphic drawing of family history, is the most important component in such a program. In this project, we analyzed the current pedigree displays of Kinsys0 ...

Background: Forensic dentistry, a branch of forensic sciences, identify suspects with the uniqueness of oral and maxillofacial structures. Lip prints and palmprints are unique. Aims and objectives: The present study was carried out with the objectives of evaluating the correlation between lip prints and palmprints and heritability of lip prints and palmprints among parents and their off springs...