Recent asthma recommendations advocate the use of long-acting beta-agonists (LABAs) in uncontrolled asthma, but also stress the importance of stepping down this therapy once asthma control has been achieved. The objective of this study was to evaluate downtitration of LABA therapy in pediatric patients who are well-controlled on combination-inhaled corticosteroid (ICS)/LABA therapy. Clinical an...

Introduction: Childhood asthma is a serious health problem that results in impairment of physical and social life the affected children. Objective: The current study identifies effect on asthmatic children quality also to assess differences between childs parents report about health, emotional activity. Method: A cross-sectional, descriptive, quantitative was carried out where Sixty-four partic...

Under the auspices of Russian Association Allergists and Clinical Immunologists Pediatric Respiratory Society, an expert meeting "Leukotriene receptor antagonists in treatment bronchial asthma" was held. Asthma is a common non-communicable chronic disorder airways characterized by variable recurring symptoms, airflow obstruction, hyperresponsiveness, underlying inflammation. The creation widesp...

Current national and international asthma guidelines recommend treatment of children with asthma towards achieving and maintaining asthma control. These guidelines provide more stringent recommendations to increase therapy for patients with uncontrolled asthma in order to reduce asthma-related morbidity and mortality. Newer combination agents such as budesonide and formoterol have been shown to...

Asthma is the most common chronic childhood disease and has seen increasing prevalence worldwide. While there is existing evidence of familial and other risk factors for pediatric asthma, there is a need for further studies to explore and understand interactions among these risk factors. The goal of this study was to develop an approach for mining, visualizing, and evaluating association rules ...

OBJECTIVES To operationalize a comprehensive description of attrition, including pre-inclusion, dropout, and attrition due to intermittent missing data, and to test a predictive model of attrition using a data set from a randomized controlled intervention in pediatric asthma. METHODS Participants included children, ages 4-12, diagnosed with asthma and their caregivers. Demographic variables a...

OBJECTIVES Few studies have investigated the complex relationship among asthma control, sleep problems, and health-related quality of life (HRQOL) among children with asthma. This study aimed to test the longitudinal effect of asthma control status on asthma-specific HRQOL through the mechanism of nighttime sleep quality and daytime sleepiness. METHODS The Patient-Reported Outcomes Measuremen...