Human papillomavirus (HPV) infection is the leading risk factor for cervical intraepithelial neoplasia (CIN) and cervical cancer. Detection of high-risk HPV infections might identify women who are at increased risk of development or progression of a cervical lesion and may have prognostic significance. Therefore there is considerable interest in identifying and accurately typing the viruses. PC...

PURPOSE This study examines the tumour-host immune interactions in head and neck squamous cell carcinoma (HNSCC) and their relationship to human papillomavirus (HPV) infectivity and patient survival. METHODS The adaptive and innate immune profile of surgical tumour specimens obtained from HNSCC patients was determined using qRT-PCR and immunohistochemistry. Intratumoural and invading margin l...

INTRODUCTION Human papillomavirus (HPV) is associated with more human cancers than any other virus. Many studies have investigated the association between bladder cancer and HPV but the results remain controversial. The aim of the present study is to evaluate whether HPV have an etiological role in bladder carcinogenesis among Moroccan patients. METHODOLOGY Forty-eight fresh biopsies (43 blad...

Purpose:Anunderstandingof howhematopoietic cells respond to therapy that causesmyelosuppression will help develop approaches to prevent this potentially life-threatening toxicity. The goal of this study was to determine how humanmyeloid precursor cells respond to temozolomide (TMZ)-induced DNA damage. Experimental Design:Wedeveloped an ex vivo primary humanmyeloid precursor cells model system t...