PURPOSE To identify deleterious mutations in the latent transforming growth factor-β-binding protein 2 (LTBP2) gene in sporadic patients with primary congenital glaucoma (PCG) from a Han Chinese population, which had been excluded for mutations in the CYP1B1 gene. METHODS In this retrospective case-control study, 36 coding exons and adjacent exon-intron boundaries of LTBP2 were amplified with...

BACKGROUND Primary Care Groups and Trusts (PCG/Ts) are responsible for improving the health of local populations, but there is little evidence of their strategic involvement in accident prevention. OBJECTIVE To determine the effect of providing information on local accidental injuries to PCG/Ts on the development of accident prevention strategies. METHODS The study is a randomized controlle...

Many plants respond to winter with epigenetic factors that gradually dampen repression of flowering so that they can flower in spring. The study of this process was important for the identification of the plant Polycomb group (PcG) of proteins and their role in the epigenetic control of plant gene expression. Fittingly, these studies continue to illuminate our understanding of PcG function. We ...

Procedural Content Generation (PCG) used to be a method to circumvent technical limitations; at the present time PCG serves to automate and leverage potential surpluses of computing power. In this paper, I describe and recreate relevant antecedents to methods of PCG in game design, in order to better understand their use in the past and present. My research methods straddle both critical readin...

Abstract. Mapping the distribution of plastic covered greenhouses (PCG) is essential for any attempts to manage these complex areas intensive agriculture. It therefore important understand how spectrum different PCG varies in order establish its unique absorption features and can be utilised mapping from remote sensing imagery. This paper presents an analysis surface reflectance values satellit...

Polycomb Group (PcG) proteins are best-known for maintaining repressive or active chromatin states that are passed on across multiple cell divisions, and thus sustain long-term memory of gene expression. PcG proteins engage different, partly geneand/or stage-specific, mechanisms to mediate spatiotemporal gene expression during central nervous system development. In the course of this, PcG prote...

We have analyzed the requirements for the multi sex combs (mxc) gene during development to gain further insight into the mechanisms and developmental processes that depend on the important trans-regulators forming the Polycomb group (PcG) in Drosophila melanogaster. mxc is allelic with the tumor suppressor locus lethal (1) malignant blood neoplasm (l(1)mbn). We show that the mxc product is dram...

In insect species that undergo long germ segmentation, such as Drosophila, all segments are specified simultaneously at the early blastoderm stage. As embryogenesis progresses, the expression boundaries of Hox genes are established by repression of gap genes, which is subsequently replaced by Polycomb group (PcG) silencing. At present, however, it is not known whether patterning occurs this way...

The phonocardiograms (PCGs), recording of heart sounds, have many advantages over traditional auscultation in that they may be replayed and analyzed for spectral and frequency information. PCG is not a widely used diagnostic tool as it could be. One of the major problems with PCG is noise corruption. Many sources of noise may pollute a PCG signal including lung and breath sounds, environmental ...

Polycomb group (PcG) proteins form at least two key complexes, namely polycomb repressive complex 1 and polycomb repressive complex 2. These complexes are involved in the progression of various cancers. Systematic research has not been conducted on the aberrant expression of PcG members in gliomas. Using the Chinese Glioma Genome Atlas data set, PcG expression patterns between normal brain tiss...