A new method for determination of pyrethroids, pyrethrins, and piperonyl butoxide (PBO) by high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS) was developed for aquatic sediments. The method detection limits for pyrethroids (15 compounds), pyrethrins, and PBO ranged from 0.16 to 1.50 ng/g sediment, which was suitable for detecting these chemicals at environmentally ...

OBJECTIVE This study determined whether two different formulations of hormone therapy (HT): oral conjugated equine estrogens (o-CEE; 0.45 mg/d, n = 209), transdermal 17β-estradiol (t-E2; 50 μg/d, n = 201) plus cyclic progesterone (Prometrium, 200 mg) or placebo (PBO, n = 243) affected sleep domains in participants of the Kronos Early Estrogen Prevention Study. METHODS Participants completed t...

Lead-rich intermediate phases, in particular Pt,,Pb and PbO, are found to form on Pt(ll1) atop Ti-buffered Si substrates prior to formation of Pb(Zr, -*TiX)O3 (PZT) thin films. Pt,_,Pb is a [ill] textured transient intermetallic phase that nucleates PZT[111] texture. PbO is a [OOl] textured layer compound that nucleates PZT[100] texture. The formation conditions and lattice matching of these in...

Methods The clinical trial design and results in adult patients were previously reported for asthma (NEJM 2013;368:2455) and AD (JID 2013;133:S177-S178). In the asthma study, inhaled glucocorticoids and long-acting beta-agonist were withdrawn after week 4 [W4] of 12 weeks of qw DPL [300 mg] or placebo [PBO]. Asthma exacerbation occurrence was the primary endpoint. Fractional exhaled nitric oxid...

The electrochemical performance of electrodeposited Ti/β-PbO 2 and Ti-Pt/β-PbO 2 anodes was galvanostatically evaluated (batch mode, 50 mA cm) to degrade the Direct Yellow 86 dye (100 or 200 mg L in 0.1 mol L Na 2 SO 4 + 1.5 g L NaCl), investigating the effect of pH and temperature. Similar results were obtained for both electrodes and the best conditions for removal of color and chemical oxyge...

Multi-Objective Combinatorial Optimization (MOCO) problems find a wide range of practical application problems, some of which involving Boolean variables and constraints. This paper develops and evaluates algorithms for solving MOCO problems, defined on Boolean domains, and where the optimality criterion is lexicographic. The proposed algorithms build on existing algorithms for either Maximum S...

The aim of this study was to determine the effect of prolonged 11β-hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibition on basal and hormone-stimulated glucose metabolism in fasted conscious dogs. For 7 days prior to study, either an 11β-HSD1 inhibitor (HSD1-I; n = 6) or placebo (PBO; n = 6) was administered. After the basal period, a 4-h metabolic challenge followed, where glucagon (3×-basal),...

Use of pyrethroid pesticides, which are highly toxic to aquatic organisms, has increased substantially over the past decade. In 2006, the pyrethroid pesticides cyfluthrin and permethrin were measured in Sacramento-San Joaquin (SSJ) Delta (CA, USA) water at 5 and 24 ng/L (pptr), respectively. To elucidate any interactions between the two pyrethroids, a 10-d laboratory exposure was performed with...

OBJECTIVE The aim of this study was to investigate the percutaneous penetration of lead oxide (PbO) powder and the effect of rapid skin decontamination with two different detergents. METHODS Franz cells were used to study in vitro PbO skin penetration through human skin during a 24-hour period. The tests were performed without or with decontamination using either Ivory Liquid soap or a new ex...