BACKGROUND Nickel, cobalt and chromium are some of the most common causes of type IV sensitizations and subsequent allergic contact dermatitis. Accurate diagnosis of contact sensitization to these metal salts is made possible through standardized patch testing; however, patch tests with metal allergens may be influenced by meteorological conditions at the time of testing. We aimed to investigat...

Contact allergy, viz. allergic contact dermatitis, photo-allergic contact dermatitis and contact urticaria, is a well-studied sub-specialty of dermatology in Singapore. Over the years, numerous studies and anecdotal reports on the subject have been published in both international and local refereed journals. This article reviews the epidemiological data on patch testing and photo-patch testing ...

D'Alcamo et al. astutely highlighted a potential immunologic association between nickel allergy, determined by positive epicutaneous patch testing, and the rise of non-celiac wheat sensitivity (NCWS) in the world of gluten-related diseases. Consecutive algorithms including both patch and intradermal testing could provide vital information to more accurately define the patient populations with N...

Assessment of a patient with probable allergic contact dermatitis caused by a tattoo ink is a difficult task, because regulations regarding the substances used as tattoo inks continue to be limited, and ink component information is difficult to access (1). Moreover, in most cases, patch testing with the culprit ink is often of little benefit. We report a case in whom patch testing with the ink ...

Parabens, methyl, ethyl, propyl, benzyl, and butyl, are the most common preservatives in use today. They are the alkyl esters of p-hydroxybenzoic acid and are used extensively because they are relatively nonirritating and nontoxic and offer good antimicrobial coverage. Testing for paraben allergen can be done by patch testing. Two cases of allergic contact dermatitis (ACD) to parabens are used ...

Type IV hypersensitivity eye reactions have been described after the administration of the sympathomimetic agent phenylephrine. We report the case of an atopic woman who developed nasal congestion and discharge, dysphagia, and dyspnea 1 hour after the administration of Stopcold pills and Disneumon Pernasal nasal spray for otitis. The same symptoms reappeared after the accidental administration ...

BACKGROUND Footwear dermatitis represents a common but often undiagnosed or misdiagnosed condition. Patch testing aids in its confirmation and identification of the offending allergen. AIMS This study aimed to find the frequency of positive patch test reactions in cases with suspected allergic contact dermatitis (ACD) to footwear, as well as the common responsible allergens. MATERIALS AND M...

One of the most important adverse consequences of patch testing is active sensitization, when subjects previously not allergic become sensitized to one or more of the test chemicals by the test procedure. The allergic test reaction then shows up about 10 or more days (late reaction) after the test application. Sometimes, however, late reactions are seen without active sensitization being presen...