In this work, we introduce a novel method for enhanced particle filtration using shear-modulated inertial migration in straight microchannels. Depending on their size, inertial lift causes particles to migrate toward microchannel walls. Using microchannels with high aspect ratio cross sections, the fluidic shear can be modulated, resulting in preferential equilibration of particles along the lo...

Porous membranes have been fabricated based on the development of the perforated membrane mold [Y. Luo and R. N. Zare, Lab Chip, 2008, 8, 1688-1694] to create a single filter that contains multiple pore sizes ranging from 6.4 to 16.6 µm inside a monolithic three-dimensional poly(dimethylsiloxane) microfluidic structure. By overlapping two filters we are able to achieve smaller pore size opening...

(1) High-efficiency particulate air (HEPA) filtration: the HEPA-filtration system used a prefilter screen, a bag filter (Eurovent [EU] 8 rating), and a HEPA filter (EU13 rating). (2) 2×-low-cost filtration: The low-cost-filtration system contained mosquito netting (prefilter), 2 fiberglass furnace filters, and 2 electrostatic furnace filters. (3) Bag filtration: Bag filtration involved the use ...

Current models and test methods for determining filter efficiency ignore filter bypass, the air that circumvents filter media because of gaps around the filter or filter housing. In this paper, we develop a general model to estimate the size-resolved particle removal efficiency, including bypass, of HVAC filters. The model applies the measured pressure drop of the filter to determine the airflo...

In this study, the focus is on magnetic separation of fresh water algae Chlamydomonas reinhardtii and Chlorella vulgaris as well as marine algae Phaeodactylum tricornutum and Nannochloropsis salina by means of silica-coated magnetic particles. Due to their small size and low biomass concentrations, harvesting algae by conventional methods is often inefficient and cost-consuming. Magnetic separa...

Soot emissions from automotive applications can be reduced through on-board diesel particulate filters (DPFs): the filter gets progressively loaded by filtering the soot laden flue gases, thus causing an increasing pressure drop, until an oxidative regeneration is induced by temperature rise. Due to the complexity of the involved phenomena, a fully predictive and detailed mathematical model rep...

High aspect ratio inertial focusing channels offers high throughput portable devices thatcan remove colloidal-size particles from a continuous media for the preparation of samplesor membranes filtration are in need for point of care operations in a compact andlightweight format. This research attempts to increase concentrating efficiency by studyingparticle behavior in the c...

Food uptake of marine mussel larvae (Mytilus edulisL.) was estimated in relation to larval size, temperature (6, 12, 18°C) and food concentration (1, 2, 5 , 10, 20 and 40 Isochrysis galbana cells 1r1-I). Filtration rates were maximal at low food concentrations (between 1 and 5 cells 1r1-l). This was called 'filtration capacity' and expressed as a function of larval size. Ingestion rates reached...

Objective(s): Lipid-based nanoparticles (NLP) are PEGylated carriers composed of lipids and encapsulated nucleic acids with a diameter less than 100 nm. The presence of PEG in the NLP formulation improves the particle pharmacokinetic behavior. The purpose of this study was to prepare and characterize NLPs containing MDR1 siRNA and evaluate their cytotoxicity and cellular uptake. MDR1 siRNA coul...