During the operation of a high-speed shear wet granulator, rotation granulation components leads to emergence phenomenon particle breakage, which results in changes size. To simulate breakage process pharmaceutical powder agglomerates Hertz–Mindlin with bonding contact model was designed this study. The effects impeller speed, chopper and time on were then studied. show that formed by particles...

Fractional plasticity has been originally proposed for capturing the state-dependent nonassociated behaviour of sand, with no use state variables and additional plastic potentials. However, coarse aggregates, significant particle breakage would occur, which could influence stress-strain material, by shifting critical line in e <...

This paper presents the results of X-ray CT imaging of the microstructure of sand particles subjected to high pressure one-dimensional compression leading to particle crushing. A high resolution X-ray CT machine capable of in situ imaging was employed to capture images of the whole volume of a sand sample subjected to compressive stresses up to 79.3 MPa. Images of the whole sample obtained at d...

We use shear-reversal simulations to explore the rheology of dense, non-Brownian, noninertial, suspensions, resolving lubrication forces between neighboring particles and modeling particle surface contacts. The transient stress response to an abrupt reversal of the direction of shear shows rate-independent, nonmonotonic behavior, capturing the salient features of the corresponding classical exp...

HE induction of crossing over in the male of Drosophila melanogaster has T been reported by PATTERSON and SUCHE (1934), who concluded that i t occured in the growth stages of the spermatocytes. This conclusion was based on the assumption that, were the crossing over taking place in pre-spermatocyte stages (that is, spermatogonia or stem cells), its rate should be highest in the youngest age irr...

Exposure to urban airborne particles is associated with an increase in morbidity and mortality. There is little experimental evidence of the mechanisms involved and the role of particle composition. We assessed cytotoxicity (crystal violet assay), apoptosis [terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) or annexin V assay], DNA breakage (comet assay), and product...

To investigate the mechanical energy applying to particles in a grinding process using planetary ball mill, impact of was estimated by simulating behavior and balls discrete element method (DEM) under different conditions size number particles, corresponding their variations during milling. As contributing particle breakage, we focused on generated at particle-to-grinding ball/wall particle-to-...